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etriosis Fertility Index (EFI),第二十七頁,共六十頁。,Least Function Scoring System (LF Score),For each side, each tube, fimbria, and ovary was scored intraoperatively following any surgical treatment based on its estimated capability to function postoperatively to create a pregnancy.,The scoring system was: 4 = Normal 3 = Mildly dysfunctional 2 = Moderately dysfunctional 1 = Severely dysfunctional 0 = Absent or nonfunctional,第二十八頁,共六十頁。,The Least Function (LF) score was calculated as the sum of the right and left lowest score assigned to the tube, fimbria, or ovary. The score therefore ranges from 0(both sides absent or nonfunctional) to 8 (both sides normal),LF Score,4 = Normal 3 = Mildly dysfunctional 2 = Moderately dysfunctional 1 = Severely dysfunctional 0 = Absent or nonfunctional,第二十九頁,共六十頁。,Estimated Cumulation Pregnancy Rates For Each Endometriosis Fertility Index (EFI) (n=1,015),第三十頁,共六十頁。,第三十一頁,共六十頁。,內(nèi)異癥不育(b249。 y249。)的治療對策,腹腔鏡手術(shù)(shǒush249。)是最好的治療(Laparoscopy) 助孕技術(shù)是最好的治療(ART) 多種因素的考慮(MultiFactors) 方案的個(gè)體化(Individuality),第三十二頁,共六十頁。,腹腔鏡手術(shù)(shǒush249。)是最好的治療,明確診斷、臨床分期(rASF)及妊娠評估 分離粘連、恢復(fù)(huīf249。)解剖、造口 創(chuàng)傷小,痛苦少,恢復(fù)快 妊娠率3080%,期別間差異不顯著 (I期36.4%,II期31.8%,III期33.3%,IV期46.4%) 反復(fù)手術(shù)不可取(卵巢損害),第三十三頁,共六十頁。,期待6個(gè)周期(zhōuqī) 受孕率 24% 治療小于3個(gè)周期 受孕率 可達(dá) 37.4%,7th GnRHa Symposium 2003,對EM不孕(b249。 y249。n)者期待是不明智的 積極治療是值得推崇的,第三十四頁,共六十頁。,Lap + GnRHa 6個(gè)月 12個(gè)月 妊娠(r232。nshēn)率相當(dāng)于單純Lap 12個(gè)月 24個(gè)月,7th GnRHa Symposium 2003,僅僅(jǐnjǐn)用 Lap 也是不夠的 Lap + GnRHa 效果好,第三十五頁,共六十頁。,藥 物 治 療,單純藥物治療不改善生育狀況 復(fù)發(fā)率高,只能緩解(huǎn jiě)EM癥狀 手術(shù)+藥物可減少復(fù)發(fā) GnRHa是重癥EM治療和助孕準(zhǔn)備的重要選擇,第三十六頁,共六十頁。,輔助生育技術(shù)(Assisted Reproductive Techniques, ART)是積極的、重要的解決內(nèi)異癥不育(b249。 y249。)的措施,比較(bǐji224。o) COH/AIH Vs IVF/ET 控制性促排卵(Controlled Ovarian Hyperstimulation, COH) 丈夫精液授精(Artificial Insemination by