dexmedetomidine對(duì)於止血帶所引起術(shù)中高血壓的療效及藥理機(jī)轉(zhuǎn)之探討(編輯修改稿)
2025-06-21 22:41 本頁(yè)面
【文章內(nèi)容簡(jiǎn)介】 uth ? Limited amnestic effect ? Excessive sedation ? Reduction in CBF/CMRO2 in animal model Dexmedetomidine 的使用 (Adult) ? Heart block 心房心室傳導(dǎo)阻滯的病患，要小心使用 ? Administer loading dose slowly 第 1個(gè)劑量要慢慢給 – Transient vasoconstriction mediated by α2Badrenoceptors will ↑ BP – loading : 1 mcg/kg over 10 min – maintenance : to mcg/kg/hr – Onset: 5 10 min – Reduced effect: 30 min – Duration: 2 hour Tournique induced hypertension ? Incidence: 30% ? Tourniquet time 60 min ? Associated with severe pain and augmented sympathetic outflow ? Difficult treatment ? Unknown mechanism Previous study data ? Ketamine ( Satsumae et al. Aamp。A, 2022) ? Clonidine ( Zalunardo et al. Aamp。A, 2022) ? Dextromethrophan ( Yamashita et al. Aamp。A, 2022)
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