【正文】
1 容量 時間曲線 2 3 4 5 6 SEC VT 800 ml 1 Inspiration 容量 時間曲線 2 3 4 5 6 SEC VT 800 ml 1 Expiration 容量 時間曲線 容量 時間曲線的臨床意義 ?肺內氣體陷閉 ?呼吸回路漏氣 壓力 容積環(huán) ?水平軸描述壓力,縱軸描述容量 0 20 40 60 20 40 60 P aw cmH20 V T LITERS 壓力 容積環(huán) 0 20 40 60 20 40 60 P aw cmH20 V T LITERS 指令呼吸 Inspiration 0 20 40 60 20 40 60 P aw cmH20 V T LITERS Inspiration Expiration 指令呼吸 壓力 容量環(huán) Volume Pressure Volume Pressure 0 20 40 60 20 40 60 P aw cmH20 V T LITERS 自主呼吸 Inspiration Expiration 0 20 40 60 20 40 60 P aw cmH20 V T LITERS Inspiration Expiration 輔助呼吸 0 20 40 60 20 40 60 P aw cmH20 V T LITERS 這是? 0 20 40 60 20 40 60 P aw cmH20 V T LITERS Dotted loop changes to solid loop any ideas? 0 20 40 60 20 40 60 P aw cmH20 V T LITERS Indicates a drop in Compliance (higher pressure for the same volume) Did you say changing pliance? 0 20 40 60 20 40 60 .2 .4 P aw cmH20 V T LITERS .6 C D A B What does this represent? What is A? What is B? What is C? And how about D? 0 20 40 60 20 40 60 P aw cmH20 V T LITERS “ D” = Lower Inflection Point A B “ A” represents PEEP “ B” Represents Inspiratory Pressure 過度膨脹 .6 .2 .4 “ C” = Upper Inflection point 最佳 PEEP V P PEEP: 3 cmH2O V P PEEP: 8 cmH2O Changing Lung Volume in CV: Paw = Lung Volume 臨床應用: ?計算吸氣面積 ?計算順應性 ?計算阻力 ?評估肺泡過度膨脹 ?衡量壓力支持水平及其做功 典型的 PV環(huán) Volume Pressure Volume Pressure Volume Pressure Controlled Assisted Spontaneous 評估吸氣流速 Volume Volume Pressure Pressure Normal Insufficient Flow Pressure Volume Loops Cusping 過度膨脹 ? Overdistension occurs when the volume limit of some ponents of the lung has been exceeded ? Abrupt decrease in pliance at the termination of inspiration ? Results in a terminal “Beaking” of the P/V Loop Volume Pressure Volume Pressure Zone of Overdistention “ Safe” Window Zone of Derecruitment and Atelectasis Injury Injury 最佳肺容量(安全窗) ? 膨脹過度 ?肺泡痿陷 Mean Airway pressure 25 cm H2O CT Scan : ARDS pig model 30 kg Optimized Lung Volume Strategy: Mean Airway Pressure 40 cm H2O CT Scan : ARDS pig model 30 kg Optimized Lung Volume Strategy: CDP= FRC CT 1 CT 2 CT 3 Paw = CDP Continuous Distending Pressure 急性呼衰時 VP曲線拐點的意義 ?上拐點提示:壓力導致局部肺泡過度膨脹 ?下拐點代表:使肺泡開始打開的最小壓力 Volume Pressure LPIflex UPIflex 容積 流速環(huán) 流速 容量環(huán) Volume Flow Volume Flow 臨床應用 ?評價支氣管擴張劑的療效 ?評估是否漏氣 ?評估吸氣阻力和呼氣流速受阻 F V V F After Suction Before Suction 氣道阻塞 重度阻塞 漏氣 Volume Pressure Volume Flow Volume Time 謝謝!