藥理學ppt課件南開大學第十五章影響自體活性物質(zhì)的藥物-資料下載頁
2025-10-09 19:54本頁面
【正文】 le) and possible teratogenic effects. H1 receptor antagonists Histamine and its agonists Histamine antagonists H1 receptor antagonists H2 receptor antagonists H2 receptor antagonists ?Chemistry amp。 Pharmacokiics ?Cimetidine ?Ranitidine ?Famotidine ?Nizatidine H2 receptor antagonists ?Pharmacodynamics ?Acid secretion and gastric motility ?Cardiovascular system ?immunological regulation Receptor Subtype Effects after being activated H1 bronchoconstriction and contraction of intestinal . Expand blood vessel Permeability↑ stimulate sensory nerve endings H2 Cause gastric acid, gastric pepsin and intrinsic factor production. Cause a decrease in systolic and diastolic blood pressure and a increase in heart rate. H2 receptor antagonists ? Peptic Duodenal Ulcer and Gastric ulcer ? Erosive Esophagitis ? Hypersecretory Conditions ?Clinical Uses H2 receptor antagonists ?Toxicity Gastrointestinal reaction, CNS reaction, Endocrine system reaction Cytochrome P450 inhibition
教學課件相關推薦
鄂ICP備17016276號-1