血栓性微血管病的診治-資料下載頁
2024-11-04 05:47本頁面
【正文】 pulmonary hypertension in patients with carcinoma,Nihon Shokakibyo Gakkai Zasshi.2022 Jul。111(7):1399407,第四十九頁，共五十四頁。,PTTM,3 cases of PTTM that presented as the initial manifestation of metastatic gastric adenocarcinoma with TMA and pulmonary infiltrates moderate thrombocytopenia without renal failure, hemolysis with extremely high serum lactate dehydrogenase levels, leukoerythroblastosis in peripheral blood smear, and interstitial pulmonary infiltrates. All patients died within 2 weeks of diagnosis. Two cases were initially misdiagnosed as idiopathic thrombotic thrombocytopenic purpura and treated with plasma exchange with no response. One patient had bone marrow infiltration by malignant cells.,Medicine〔Baltimore).2022 Nov；93〔24〕：35963,第五十頁，共五十四頁。,PTTM,lateletderived growth factor (PDGF) and vascular endothelial growth factor (VEGF) may play important roles in the pathogenesis of PTTM treated with a combination therapy of imatinib (PDGF receptor antagonist), bevacizumab (VEGF receptor inhibitor〕 suggest that moleculartarget drugs are effective for the treatment of PTTM,InternMed.2022；53〔22〕25959,第五十一頁，共五十四頁。,CRTMA,17 patients who had TMAs associated with disseminated solid cancer over an 11year period compared them with a group of 20 patients with proven idiopathic thrombotic thrombocytopenic purpura clues to the presence of CRTMA include respiratory symptoms, bone pain, myelemia or higher platelet count than in thrombotic thrombocytopenic purpura bone marrow aspiration is a fast and gainful investigation to avoid plasmatherapy and immunosuppressive drugs,Future Oncol 2022 Aug。10(10):172734,第五十二頁，共五十四頁。,Thank you,第五十三頁，共五十四頁。,內(nèi)容(n232。ir243。ng)總結(jié),血栓性微血管病的診治。腎小動脈可見血管腔內(nèi)血栓形成及管腔閉塞，進而引起局灶或廣泛的腎內(nèi)質(zhì)壞死。凝血功能檢查如凝血酶原時間及局部凝血激酶時間通常正常。84％～92％，較重。CsA可以增加(zēngjiā)血小板聚集、血栓素A2的產(chǎn)生，高濃度CsA水平還與血栓調(diào)理素及vWF水平相關(guān)。正常人ADAMTSl3血漿活性為79％～127％。遺傳性TTP患者ADAMTS13活性降低程度與疾病嚴重程度相關(guān)。Thank you,第五十四頁，共五十四頁。,
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