【正文】 13(9): 1019–1027 In pts treated with CRTD devices capable of daily transmission of their diagnostic data via Home Monitoring， this tool may increase pts’ quality of life and reduce morbidity, mortality, and health economic burden, it now warrants prospective studies 小 結 ? CRT已成為治療心衰患者的重要手段，但仍有部分患者無應答或由于術后管理不充分而導致心血管事件 ?CRT的心力衰竭監(jiān)護系統(tǒng)相比傳統(tǒng)門診隨訪模式能夠及時識別患者心衰病情變化和監(jiān)測 CRT治療的有效性 ?不斷發(fā)展的心衰監(jiān)測工具將進一步幫助臨床醫(yī)生早期預測心衰加重，更好地降低患者住院率和死亡率 。 13(9): 1019–1027 HomeCARE II急性失代償性心衰 ICD 隨訪后住院 Eur J Heart Fail. 2020。12:702707 Conclusion In HF patients, a strong correlation between changes in intracardiac impedance and LV SV was found. Typical LV lead implant positions have been tested and all appear to be suitable for this method of LV volume monitoring. Potential value of automated daily screening of CRTD diagnostics for prediction of major cardiovascular events: results from HomeCARE 研究目的 在患者出現(xiàn)心衰相關事件同時長期記錄經胸阻抗 通過回溯評估敏感性和假陽性率來完善阻抗監(jiān)測算法 進一步提高心衰監(jiān)測系統(tǒng)表現(xiàn) 研究設計 多中心，國際性 終點事件驅動 Eventdriven (35 HF相關事件 ) 預期 60 HF事件 預期 600 所有事件 研究時間表 首例植入 : 入組 : – 隨訪 : 3, 9, 15, 21 月 最后病例結束 : ~ . 入組患者 ~300 患者 , NYHA IIIV LVEF ? 35% 高心衰住院風險 Lumax 540 (VR,DR,HF) Eur J Heart Fail. 2020。12:702707 Haemodynamic effects of overdrive pacing Bocchiardo M et al. Europace 2020。 AortaP, aortic blood pressure。12:702707 ?14 pts with DCM， one or two suitable implantation sites for the LV lead were selected. Following atrial, RV, and LV catheter positioning, a micromanometer catheter was placed in the ascending aorta ?At each LV lead position, a pacing protocol was performed with biventricular pacing in DDD mode, AV delay 100 ms, and VV delay 0 ms. pacing rates 80, 100, 120, 140, and 40 ppm ?correlation between SV and intracardiac SZ has been investigated during a biventricular pacing ?Different CS lead implantation sites have been used, but RV lead position was always apical Patient LV position SZ–SV SZ–PP R σ (%) R σ (%) 1 Apical * 17 * 17 1 Medial lateral * 17 * 17 2 Medial posterior * 15 * 14 2 Medial anterior * 20 * 21 3 Medial lateral * 16 * 22 3 Medial posterior * 12 * 13 4 Medial lateral * 6 * 4 4 Medial anterior * 15 * 17 5 Medial posterior * 31 * 32 6 Medial posterior * 23 * 24 6 Medial posterior * 29 * 28 7 Medial lateral * 14 * 13 7 Apical * 66 * 66 8 Medial lateral * 26 * 24 9 Basal anterior . 46 . 50 10 Basal lateral * 9 * 9 11 Medial lateral . 34 . 33 12 Basal lateral * 9 * 9 13 Medial posterior * 11 * 12 14 Medial posterior * 8 * 9 Mean 21 22 SD 15 15 Bocchiardo M et al. Europace 2020。 2%, P ) was significantly increased after 6m of CRTD implantation ?No significant changes were detected in any parameters in group A ?These data showed intrathoracic impedance changes reflected reverse LV remodeling in response to CRT in patients with CHF Int Heart J. 2020。 12 mL, P ) were significantly decreased， LVEF (28 177。 14 mL, P ), LVESV (128 177。 70 pg/mL, P ), LVEDV (177 177。 12 years) with CRTD ?Optivol Fluid Index 60 ohms (group A, n = 7) ， 60 ohms (group B, n = 22) within 6m after implantation ?BNP， LVEDV, LVESV, and LVEF before and 6 m after CRTD ?In group B, BNP (556 177。 however, a similar trend was not observed for the atrial tachyarrhythmic events ?CONCLUSIONS: Intrathoracic impedance moni