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posures), or have a carboxyhemoglobin level of 25% or more. ——Undersea and Hyperbaric Medical Society, 2008.,Guidelines,A Clinical Policies Subcommittee of the American College of Emergency Physicians states that “hyperbaric oxygen is a therapeutic option for carbon monoxide–poisoned patients。 however, its use cannot be mandated… No clinical variables, including carboxyhemoglobin levels, identify a subgroup of patients for whom hyperbaric oxygen is most likely to provide benefit or cause harm.“ ——American College of Emergency Physicians,2008,中國的指南(草案,2010),推薦意見:有條件時(shí),在急性期應(yīng)盡早高壓氧治療,這樣可以加快排出體內(nèi)一氧化碳,有益于患者盡快清醒,減輕機(jī)體缺氧性損傷,降低遲發(fā)腦病發(fā)生率。 (推薦等級B級:至少有1項(xiàng)大樣本、隨機(jī)研究、結(jié)論確定,假陽性或假陰性錯(cuò)誤的風(fēng)險(xiǎn)較低。) 推薦意見:高壓氧治療壓力0.2~0.25MPa。艙內(nèi)吸氧時(shí)間60min。治療次數(shù)根據(jù)患者病情決定,但連續(xù)治療次數(shù)不超過30次。 (推薦等級C級:僅有小樣本、隨機(jī)研究、結(jié)論不確定,假陽性和∕或假陰性錯(cuò)誤的風(fēng)險(xiǎn)較高。),Conclusions and Recommendations,Patients who have had carbon monoxide poisoning should be treated immediately with normobaric oxygen. Clinicians evaluating patients with acute poisoning should consider hyperbaric oxygen therapy. Patients should be informed that they may not fully recover after poisoning. Carbon monoxide poisoning can result in permanent sequelae.[2] [2]Weaver LK. Carbon monoxide poisoning. N Engl J Med 2009。360:12171225.,Any Questions?,