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【正文】 t al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, openlabel, noninferiority study. Lancet 2008。 372:1240–1250.[11] Gill A, Hoogwerf BJ, Burger J, et al. Effect of exenatide on heart rate and blood pressure in subjects with type 2 diabetes mellitus: a doubleblind, placebocontrolled, randomized pilot Diabetol. 2010 Jan 28。916.[12] Bain S C, Stephens J W. Exenatide and pancreatitis: an update. Expert Opin Drug Saf. 2008。7(6):643–644.[13] Mari A, Degn K, Brock B, et al. Effects of the longacting human glucagonlike peptide1 analog liraglutide on betacell function in normal living conditions. Diabetes Care. 2007。30 (8):2032–2033.[14] Garber A, Henry R, Ratner R, et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD3 Mono): a randomised, 52week, phase III, doubleblind, paralleltreatment trial. Lancet. 2009。373(9662):473–481.[15] Seino Y, Rasmussen M F, Zdravkovic M, et al. Dosedependent improvement in glycemia with oncedaily liraglutide without hypoglycemia or weight gain: A doubleblind, randomized, controlled trial in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract. 2008。81(2):161–168.[16] Astrup A, Rossner S, Van G L, et al. Effects of liraglutide in the treatment of obesity: a randomised, doubleblind, placebocontrolled study. Lancet. 2009。374(9701):1606–1616.[17] Marre M, Shaw J, Brandle M, et al. Liraglutide, a oncedaily human GLP1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control pared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD 1 SU). Diabet Med. 2009。26(3):268–278.[18] Nauck M, Frid A, Hermansen K, et al. Effcacy and safety parison of liraglutide, glimepiride, and placebo, all in bination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)2 study. Diabetes Care. 2009。32(1):84–90.[19] Zinman B, Gerich J, Buse J B, et al. Effcacy and safety of the human glucagonlike peptide1 analog liraglutide in bination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD4 Met+TZD). Diabetes Care. 2009。32(7):1224–1230.[20] Engel S S, WilliamsHerman D E, Golm GT, et al. Sitagliptin: review of preclinical and clinical data regarding incidence of J Clin Pract. 2010 Jun。64(7):984990.[21] Iwamoto Y, Taniguchi T, Nonaka K, et al. DoseRanging Efficacy of Sitagliptin, a Dipeptidyl Peptidase4 Inhibitor, in Japanese Patients with Type 2 Diabetes 。57(5): 383394.[22] DeFronzo R A, Hissa M N, Garber A J, et al. The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin Care. 2009。32(9):. 若不給自己設(shè)限，則人生中就沒有限制你發(fā)揮的藩籬。2. 若不是心寬似海，哪有人生風(fēng)平浪靜。在紛雜的塵世里，為自己留下一片純靜的心靈空間，不管是潮起潮落，也不管是陰晴圓缺，你都可以免去浮躁，義無反顧，勇往直前，輕松自如地走好人生路上的每一步3. 花一些時間，總會看清一些事。用一些事情，總會看清一些人。有時候覺得自己像個神經(jīng)病。既糾結(jié)了自己，又打擾了別人。努力過后，才知道許多事情，堅持堅持，就過來了。4. 歲月是無情的，假如你丟給它的是一片空白，它還給你的也是一片空白。歲月是有情的，假如你奉獻(xiàn)給她的是一些色彩，它奉獻(xiàn)給你的也是一些色彩。你必須努力，當(dāng)有一天驀然回首時，你的回憶里才會多一些色彩斑斕，少一些蒼白無力。只有你自己才能把歲月描畫成一幅難以忘懷的人生畫卷。學(xué)習(xí)參考
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