【正文】
2016。11(2):e0148407. [22] Yuana Y, Sturk A, Nieuwland R. Extracellular vesicles in physiological and pathological conditions. Blood Rev. 2013。 27:3139.[23] Sunkara V, Woo HK, Cho YK. Emerging techniques in the isolation and characterization of extracellular vesicles and their roles in cancer diagnostics and prognostics. Analyst. 2015.[24] Iraci N, Leonardi T, Gessler F, et al. Focus on extracellular vesicles: physiological role and signalling properties of extracellular membrane vesicles. Int J Mol Sci. 2016。17(2):171. [25] Ratajczak J, Miekus K, Kucia M, et al. Embryonic stem cellderived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia. 2006。20(5):847856.[26] Takahashi K, Yan IK. Involvement of extracellular vesicle long noncoding RNA (lincVLDLR) in tumor cell responses to chemotherapy. Mol Cancer Res. 2014。12(10):13771387. [27] Collino F, Deregibus MC, Bruno S, et al. Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs. PLoS One. 2010。5(7):e11803.[28] Mause SF, Weber C. Microparticles Protagonists of a Novel Communication Network for Intercellular Information Exchange. Circ Res. 2010。107(9):10471057.[29] Li L, Piontek K, Ishida M, et al. Extracellular vesicles carry miR195 to intrahepatic cholangiocarcinoma andimprove survival in a rat . 2016.[30] Helbing T, Olivier C, Bode C, et al. Role of microparticles in endothelial dysfunction and arterial hypertension. World J Cardiol. 2014。6(11):11351139.[31] Zakharova L, Svetlova M, Fomina AF. T cell exosomes induce cholesterol accumulation in human monocytes via phosphatidylserine receptor. J Cell Physiol. 2007。212:174181.[32] Chaput N, Th233。ry C. Exosomes: immune properties and potential clinical implementations. Semin Immunopathol. 2011。 33:419440.[33] MontoroGarc237。a S, Shantsila E, Tapp LD, et al. Smallsize circulating microparticles in acute coronary syndromes: relevance to fibrinolytic status, reparative markers and outes. Atherosclerosis. 2013。227(2):313322.[34] Lorenzen JM, Thum T. Circulating and urinary microRNAs in kidney disease. Clin J Am Soc Nephrol. 2012。7(9):15281533.[35] Fleitas T, Mart237。nezSales V, Vila V, et al. Circulating endothelial cells and microparticles as prognostic markers in advanced nonsmall cell lung cancer. PLoS One. 2012。7(10):e47365.[36] Melo SA, Luecke LB, Kahlert C, et al. Glypican1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2015。523(7559):177182.[37] Bank IE, Timmers L, Gijsberts CM, et al. The diagnostic and prognostic potential of plasma extracellular vesicles for cardiovascular disease. Exp Rev Mol Diagn. 2015。15(12): 15771588. [38] Wisgrill l, Lamm C. Peripheral blood microvesicles secretion is influenced by storage time, temperature, and anticoagulants. Cytometry A. 2016。89(7):663672.[39] Ong SG, Wu JC. Exosomes as potential alternatives to stem cell therapy in mediating cardiac regeneration. Circ Res. 2015。 117:79. [40] Ong SG, Lee WH. Cross talk of bined gene and cell therapy in ischemic heart disease role of exosomal microrna transfer. circulation. 2014。130(suppl 1):S60S69.[41] Lai RC, Yeo RW, Tan KH, et al. Exosomes for drug delivery a novel application for the mesenchymal stem cell. Biotechnol Adv. 2013。31:543551.[42] Yim N, Ryu SW. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible proteinprotein interaction module. Nat Commun. 2016。7:12277.[43] Ohno S, Takanashi M, Sudo K, et al. Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells. Mol Ther. 2013。21(1):185191.[44] Ibrahim AG, Cheng K, Marb225。n E. Exosomes as critical agents of cardiac regeneration triggered by cell therapy. Stem Cell Reports. 2014。2(5):606619. 完美WORD格式編輯