【正文】
with 4phosphopantetheine with 4phosphopantetheine 3. Enzymes acetyl CoA carboxylase 4 enzymes fatty acid synthetase (multifunctional enzyme) 4. 2 Cs two carbons from release two carbons as malonyl CoA acetyl CoA 5. Coenzymes NADPH NAD+, FAD 6. Product palmitate acetyl CoA Triacylglycerols of triacylglycerol lipases lipases lipases of Glycerol (Glycerol can be metabolized in the liver, kidney, and intestine, but not in adipose tissue and skeletal muscle) CH2OHCHOHCH2OHglycerolg l y c e r o k i n a s eA T P A D PC H 2 O HC HO HC H 2 O Pg lyc er o l 3 p h o sp h a t e α g l y c e r o l 3 p h o s p h a t e d e h y d r o g e n a s eN A D + N A D H + H +C H 2 O HC = OC H 2 O Pd i h y d r o x y a c e t o n e p h o s p h a t eG ly c o ly s isg lu c o n e o g e n e s isend G CH2OH C=O CH2O P NADH+H+ NAD+ Glycerol3P dehydrogenase CH2OH C CH2O HO— P CH2OCOR1 C CH2O R2COO— P CH2OCOR1 C CH2OH R2COO CH2OCOR1 C CH2OCOR3 R2COO— CoASH R3CO~SCoA R1CO~SCoA R2CO~SCoA acyltransferase 2 CoASH phosphatidic acid of triacylglycerols Problem ? What are the differences between ?oxidation and biosynthesis of fatty acid? ? Describe the processes of ?oxidation.