20xx年醫(yī)學(xué)專題—第四十三章人工合成抗菌藥(編輯修改稿)
2024-11-16 00:59 本頁面
【文章內(nèi)容簡介】 e，痢特靈),硝基(xiāo jī)咪唑類藥物 Nitroimidazoles,甲硝唑(metronidazole, 甲硝噠唑, 滅滴靈),第二十二頁，共三十五頁。,抗菌藥物作用(zu242。y242。ng)機制示意圖,第二十三頁，共三十五頁。,Clinical Use of antibacterial agents,第二十四頁，共三十五頁。,Communityacquired Shigella N.gonorrhea H.influenzae M.catarrhalis S.pneumoniae Hospitalacquired S.aureus VRSA Enterococci Enterobacteriaceae,MRSA,VRE,ESBL,,Major resistance problems,1940 1950 1960 1970 1980 1990 2000,第二十五頁，共三十五頁。,MRSA – HA vs. CA,Community acquired (CA) MRSA Younger population. More likely to produce skin and soft tissue infections. Not multidrug resistant. Healthcare associated (HA) MRSA Multidrug resistant. Associated with foreign bodies.,Multidrug resistance is a condition enabling a diseasecausing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at eradicating the organism.,第二十六頁，共三十五頁。,Treatment,Vancomycin Clindamycin Bactrim Te
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