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【正文】 一頁(yè)，共三十五頁(yè)。,分 類,第十三頁(yè)，共三十五頁(yè)。o) 桿菌：大腸埃希菌、布魯斯菌、變形桿菌等 衣原體 放線菌 傷寒 瘧原蟲,第十五頁(yè)，共三十五頁(yè)。nz224。ng),易通過(tōnggu242。,3.不良反應(yīng),（1）損害(sǔnh224。ng)機(jī)制,二氫葉酸還原酶,二氫葉酸(y232。,抗菌機(jī)制(jīzh236。nɡ)應(yīng)用,第二十一頁(yè)，共三十五頁(yè)。y242。,MRSA – HA vs. CA,Community acquired (CA) MRSA Younger population. More likely to produce skin and soft tissue infections. Not multidrug resistant. Healthcare associated (HA) MRSA Multidrug resistant. Associated with foreign bodies.,Multidrug resistance is a condition enabling a diseasecausing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at eradicating the organism.,第二十六頁(yè)，共三十五頁(yè)。,Principles of antibacterial use,Antimicrobial agents combination Drug categories 1.βLactam antibiotics 2. Aminoglycosides 3. Tetracyclines, macrolide, chloramphenicol 4. Sulfonamides 1+2: Synergism 1+3:antagonism 2+3:synergism or plus 3+4: plus,第三十頁(yè)，共三十五頁(yè)。,第三十四頁(yè)，共三十五頁(yè)。甲氧芐啶類：甲氧芐啶(trimethoprim)。抑制DNA回旋酶而影響細(xì)菌DNA的合成
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