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Lucchesi C,et Evidence of increased restless legs syndrome occurrence in chronic and highly disabling migraine. Functional Neurology,2012。 27(2): 9194,第十七頁,共三十四頁。,偏頭痛與抑郁(y236。y249。),偏頭痛 OR=2.35~3.22 除了偏頭痛發(fā)作(fāzu242。)頻率外,CA列第二位,Breslau N,Davis GC. Migraine physical health and psychiatric disorder: a prospective epidemiologic study i n young adults. J Psychiatr Res, 1 993,27:211221. Louter M1, Wardenaar K, Veen G,et al.Allodynia is associated with a higher prevalence of depression in migraine patients.Cephalalgia,2014[Epub ahead of print] Breslau N, Schultz L R, Stewart AT, et al .Headache and major depression: is the association specific to migraine? Neurology,2000,54:308313.,第十八頁,共三十四頁。,抑郁(y236。y249。)與偏頭痛,1 OR=1.22 in mild depression (95% CI 1.10 to 1.35) OR=1.62 in severe depression (95% CI 1.34 to 1.96). 2,Louter MA1,et al.Brain,2013。136(Pt 11):348996. Bigal ME,et al.Prevalence and characteristics of allodynia in headache sufferers: a population study.Neurology,2008。70(17):152533.,第十九頁,共三十四頁。,FMS與偏頭痛,22.2% 女性偏頭痛患者伴發(fā)FMS 1 31.4% 偏頭痛患者伴發(fā)FMS,與先兆(xiānzh224。o)無關(guān)2 35%88% FMS伴發(fā)頭痛 3,伴發(fā)偏頭痛63%, MOH 8% 4,Ifergane G,et al.Prevalence of fibromyalgia syndrome in migraine patients. Cephalalgia,2006。26(4):4516. K252。231。252。k?en S,The prevalence of fibromyalgia and its relation with headache characteristics in episodic migraine. Clin Rheumatol,2013。32(7):98390. Valen231。a MM, et al.Neuroendocrine dysfunction in fibromyalgia and migraine. Curr Pain Headache Rep. 2009。13(5):35864. Marcus DA,et al.Fibromyalgia and headache: an epidemiological study supporting migraine as part of the fibromyalgia syndrome. Clin Rheumatol,2005。24(6):595601.,第二十頁,共三十四頁。,FMS與偏頭痛,5HT異常 1 興奮性氨基酸異常 2 下丘腦、腦干疼痛加工(jiā gōng)機(jī)制異常 3,Nicolodi M1, Sicuteri F.Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. Adv Exp Med Biol,1996。398:373