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ace marker Subclass Functions DevelopmentIII Natural killer cells 10minPart 3 Molecules of immune (1) CD antigens 15min(2) Adhesion molecules 20min(3) Cytokines 45minI Molecules with multiple functionsII Cytokine familiesIII Cytokines in clinic難點(diǎn)與重點(diǎn)Mechanism of NK cellmediated killing.Adhesion molecules amp。 leucocyte migrationCytokines act in a network新進(jìn)展 Chemokines and chemokines receptor. 教學(xué)手段Multimedia參考書臨床免疫學(xué)和免疫檢驗(yàn),王蘭蘭主編,人民衛(wèi)生出版社,2003醫(yī)學(xué)免疫學(xué),吳敏毓主編,中國科技大學(xué)出版社,2002Immunology (sixth edition), Roitt, Harcourt Asia Pte Ltd, 2001復(fù)習(xí)思考題The differences of killing mechanism in NK cells and CTL.The bipolar Th1/Th2 and clinical disease.講課改進(jìn)意見 教研室主任 年 月 日2005年 9月12日講課內(nèi)容 Immune response (1) 教學(xué)方式 Lecture 學(xué)時(shí) 2 教學(xué)目的 1 The concept and stage of immune response.2 T cells mediated immunity3 B cells mediated immunity授課提綱及時(shí)間分配Review 10minChapter 7. Immune responsePart 1 The concept and stage of immune response. 20minPart 2 T cells mediated immunity (1) Antigen presentation 15min(2) Activation of T Lymphocytes 20min(3) Effects of T cells mediated immunity 25minI Th1II CTL難點(diǎn)與重點(diǎn)Double recognition and dual signals.T cellsmediated cytotoxicity.新進(jìn)展 教學(xué)手段Multimedia參考書臨床免疫學(xué)和免疫檢驗(yàn),王蘭蘭主編,人民衛(wèi)生出版社,2003醫(yī)學(xué)免疫學(xué),吳敏毓主編,中國科技大學(xué)出版社,2002Immunology (sixth edition), Roitt, Harcourt Asia Pte Ltd, 2001復(fù)習(xí)思考題Complex between TCR, MHC and peptideCytotoxicity Mechanism of CTL.Recognition of different forms of antigen by B and Tcells.講課改進(jìn)意見 教研室主任 年 月 日2005年 9月14日講課內(nèi)容 Immune response (2) amp。 Immunoregulation 教學(xué)方式 Lecture 學(xué)時(shí) 2 教學(xué)目的 1 B cells mediated immunity2 Regulation of the immune response by gene, molecules, and cells.授課提綱及時(shí)間分配Review 5minChapter 7. Immune response(2)Part 3 B cells mediated immunity (1)Activation of B cells by TIAg amp。TDAg 15min(2) Activation and differentiation of B cells in the germinal center 10min(3) Antibody response in vivo 15minChapter 8. ImmunregulationPart 1 Genetic control of immune response 5minPart 2 Regulation by antigen and antibody 10min Part 3 Regulation by immune cells 25minPart 4 Neuroendocrine modulation of immune response 5min難點(diǎn)與重點(diǎn)Differentiation of B cells in the germinal centerAffinity maturation and class switchingRegulation by immune cells新進(jìn)展 The role of regulatory T cells in immunoregulation教學(xué)手段Multimedia參考書臨床免疫學(xué)和免疫檢驗(yàn),王蘭蘭主編,人民衛(wèi)生出版社,2003醫(yī)學(xué)免疫學(xué),吳敏毓主編,中國科技大學(xué)出版社,2002Immunology (sixth edition), Roitt, Harcourt Asia Pte Ltd, 2001復(fù)習(xí)思考題Recognition of different forms of antigen by B and Tcells.How to modulate the immune response by lymphocytes?講課改進(jìn)意見 教研室主任 年 月 日2005年 9月19日講課內(nèi)容 抗原抗體反應(yīng),免疫原和抗血清制備 教學(xué)方式 理 論 學(xué)時(shí) 2 教學(xué)目的 1熟練掌握抗原抗體反應(yīng)的機(jī)理及特點(diǎn)(反應(yīng)的特異性、比例性、可逆性、階段性)和反應(yīng)類型;了解抗原抗體反應(yīng)的影響因素(抗原、抗體及反應(yīng)環(huán)境)。2熟練掌握多克隆抗體的制備流程;了解常見免疫原的制備、動(dòng)物的選擇和接種方法;掌握抗血清的鑒定