lipidmetabolism脂類合成(編輯修改稿)
2025-05-28 02:10 本頁面
【文章內(nèi)容簡介】 uced, 3. Tricarboxylic acid cycle and oxidative phosphorylation 8 acetyl CoA: 80(96) ATPs produced. Total 106(129) ATPs produced 1. From palmitate to palmitoyl CoA consumed 2 ATPs bodies ? Acetoacetate, D3hydroxybutytate and acetone are called ketone bodies. ? They are produced in the liver and provide an alternative supply of fuel for the brain under starvation conditions or in diabetes. Do you think that the young man takes 250g of butter per day for 3 days? Really! Oh, so Stupid! there must be lots of ketone bodies in his urine Fatty acid synthesis ? Overview ? Transport into the cytosol ? The pathway 1. Overview ? Fatty acid synthesis involves the condensation of twocarbon units,in the form of acetyl CoA,to form long hydrocarbon chains in a series of reactions. into the cytosol ? Since fatty acid synthsis takes place in the cytosol,the acetyl CoA produced from pyruvate has to be transported out of the mitochondria. citrate oxaloacetate pyruvate H2O ATP CO2 Acetyl CoA mitochondrion cytosol citrate oxaloacetate Acetyl CoA ATP,CoASH ADP+Pi malate pyruvate NADH+H+ NAD+ NADP+ NADPH+H+ CO2 malate Pyr carboxylase Fatty acid synthesis Palmitic acid is the first synthesized fatty acid from acetyl CoA. All other fatty acids are made by the modification of palmitic acid. Acetyl CoA Malonyl CoA palmitate Other fatty acids ① ② ③ pathway 1） Formation of malonyl CoA ATPCO2ADP + PiBiotina c e t y l C o A c a r b o x y l a s e
環(huán)評公示相關(guān)推薦
鄂ICP備17016276號-1