臨床表現(xiàn)ppt課件(編輯修改稿)
2025-02-01 04:42 本頁面
【文章內(nèi)容簡介】 ransmitted infection in epidemics Hepatitis B transmitted parenterally mothertoinfant play a key role in China blood ,blood products and body fluid others Hepatitis C and D similar to hepatitis B intravenous drug abusers most mon hepatitis C for the time being Prevalence rate in China 1992 ? Hepatitis A antiHAV+ % ? Hepatitis B HBsAg + % (2022) % ? Hepatitis C antiHCV+ % ? Hepatitis D antiHDV+ % ? Hepatitis E antiHEV+ % Pathogenesis ? Hepatocellular damage produced by viral replication directly only in hepatitis D ? Other types of viral hepatitis induced mainly by immunemediated attack on the liver Pathology ? The varying lesion could be seen in entire liver, but variable in severity and in different stages of the disease ? No specific lesion suggesting etiologic type of hepatitis virus Clinical manifestations ? Wide clinical spectrum from asymptomatic form to fatal oute such as liver failure ? Similar clinical course in different etiological type of viral hepatitis The clinical types viral hepatitis Acute hepatitis Chronic hepatitis Liver failure (severe hepatitis) Cholestatic viral hepatitis Hepatitis cirrhosis Asymptomatic virus carrier status (usually only in HBV) Incubation period Hepatitis A 26w ~4w Hepatitis E 29w ~6w Hepatitis B 16m ~3m Hepatitis C 2w6m ~ 6w Hepatitis D 420w Acute hepatitis 3 phases of the icteric hepatitis Prodromal phase ? sudden or insidious onset, lasting 37d ? constitutional symptom: malaise, fatigue, mild fever some time, dark urine ? gastrointestinal symptoms: anorexia, nausea, vomiting ? s
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