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l. A systematic review of randomized controlled trials examining the shortterm benefit of ambulatory oxygen in COPD. Chest 2007。 129:3.7. Burns BH, Howell JB. Disproportionately severe breathlessness in chronic bronchitis. Q J Med 1969。 139:1459.9. PRICE HL. Effects of carbon dioxide on the cardiovascular system. Anesthesiology 1960。 310:874.11. Kazemi H. Cerebrospinal fluid and the control of ventilation. In: The Lung: Scientific Foundations, 2nd ed, Crystal RG, West JB, Weibel ER, Barnes PJ (Eds), LippincottRaven Publishers, Philadelphia 1997. .12. Gutierrez G. Cellular effects of hypoxemia and ischemia. In: The Lung: Scientific Foundations, 2nd ed, Crystal RG, West JB, Weibel ER, Barnes PJ (Eds), LippincottRaven Publishers, Philadelphia 1997. .13. Hornbein TF. Hypoxia and the brain. In: The Lung: Scientific Foundations, 2nd ed, Crystal RG, West JB, Weibel ER, Barnes PJ (Eds), LippincottRaven Publishers, Philadelphia 1997. .14. West JB. Causes of carbon dioxide retention in lung disease. N Engl J Med 1971。 321:1223.16. Sorli J, Grassino A, Lorange G, MilicEmili J. Control of breathing in patients with chronic obstructive lung disease. Clin Sci Mol Med 1978。 71:228.18. Parot S, Miara B, MilicEmili J, Gautier H. Hypoxemia, hypercapnia, and breathing pattern in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1982。 122:191.20. O39。 167:116.21. Rudolf M, Banks RA, Semple SJ. Hypercapnia during oxygen therapy in acute exacerbations of chronic respiratory failure. Hypothesis revisited. Lancet 1977。 122:747.23. Christiansen J, Douglas CG, Haldane JS. The absorption and dissociation of carbon dioxide by human blood. J Physiol 1914。 155:609.25. Robinson TD, Freiberg DB, Regnis JA, Young IH. The role of hypoventilation and ventilationperfusion redistribution in oxygeninduced hypercapnia during acute exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000。 24:23.27. Crossley DJ, McGuire GP, Barrow PM, Houston PL. Influence of inspired oxygen concentration on deadspace, respiratory drive, and PaCO2 in intubated patients with chronic obstructive pulmonary disease. Crit Care Med 1997。 96:626.29. Bone RC, Pierce AK, Johnson RL Jr. Controlled oxygen administration in acute respiratory failure in chronic obstructive pulmonary disease: a reappraisal. Am J Med 1978。 186:235.31. Gay PC, Edmonds LC. Severe hypercapnia after lowflow oxygen therapy in patients with neuromuscular disease and diaphragmatic dysfunction. Mayo Clin Proc 1995。 23:932.33. Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2016. (Accessed on March 17, 2016).34. Durrington HJ, Flubacher M, Ramsay CF, et al. Initial oxygen management in patients with an exacerbation of chronic obstructive pulmonary disease. QJM 2005。UpToDate, Inc. All rights reserved.