【新整理】非st段抬高急性冠脈綜合征-在線瀏覽
2024-11-20 22:00本頁面
【正文】 ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Cumulative probability of death,84 ml/min,5166 ml/min,51 ml/min,P0.001, log rank,%,6684 ml/min,Aviles RJ et al NEJM 2003,Creatinine Clearance and Mortality GUSTO 4,Days,360,240,120,0,20,18,16,14,12,10,8,6,4,2,0,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,Probability of death, %,1869 ng/L,237669 ng/L, 237 ng/L,P0.001, log rank,6691869 ng/L,James S et al Circulation 2003,NTpro BNP GUSTO 4,Days,Invasive vs. Conservative Strategy for ACS Death or (re)MI,Trial N PCI Cons RITA 3 1810 7.6 8.3 VINO 131 6.3 22.4 TACTICS 2220 7.3 9.5 TRUCS 148 7.6 16.7 FRISC II 2451 10.4 14.1 MATE 201 9.9 6.7 VANQUISH 920 24.0 12.2 Overall 7876,Fox, Lancet 360:743 ‘03,Death/(re)MI,CP97174445,%,TACTICS–TIMI 18,TnT cut point = 0.01 ng/mL (54% of pt TnT +),Troponin T: Death, MI, Rehosp ACS, 6 Months,OR=0.52 *P0.001 Interaction P0.001,P=NS,*,n=414,n=396,n=463,n=495,FRISC Score and an Invasive Strategy,Score 02 34 57 n 972 1051 264 p 0.56 0.018 0.001 RR 1.14 (0.731.77) 0.69 (0.500.94) 0.44 (0.280.69),,0,5,10,15,20,25,30,35,40,Death or MI at 12 mos, % Strategy:,Noninvasive,Invasive,FRISC score Age 65 years Male gender Diabetes mellitus Previous MI STdepression Elevated troponin Elevated Il6 / CRP,Lagerqvist B et al Heart 2004,Benefits of an Invasive Strategy in NonST Elevation ACS,Only shown to reduce death and MI in high risk pts Reduces rehospitalization, angina in many others Shortens hospitalization, may be cost effective What about the optimal timing of
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