新生兒肺出血-lyjppt課件-展示頁
2025-01-28 22:06本頁面
【正文】 FiO2 increment – Mild and Severe – Mortality ? 15% moderate ? 64% severe – BPD ? 64% (moderate and severe) ? Baier et al 2022 – Clinically significant PH (moderate–severe) – Mortality 27% ? Majority from respiratory failure ? Not acutely – BPD ? 50% of survivors ? Greatly increased duration of MV and oxygen ? 100% were on Oxygen at 28 days – Survival without BPD ? 33% – CNS morbidity increased ? IVH 53% ? Increased severity of IVH ? PVL 13% Alfaleh K, Pediatrics. 2022 臨床表現(xiàn) ? 原發(fā)病表現(xiàn) ? 全身癥狀 ? 呼吸障礙 原發(fā)病癥狀基礎(chǔ)上臨床表現(xiàn)突然加重 Acute deterioration of patient who was improving post surfactant ? 出血表現(xiàn) 鼻腔、口腔流出或噴出血性液體，或于氣管插管后流出或吸出泡沫樣血性 ? 肺部體征 ： 呼吸音減低或有濕噦音 輔助檢查 ● 胸部 X線動(dòng)態(tài)表現(xiàn) √廣泛的斑片狀陰影，大小不一， 密度均勻 ，有時(shí)可有支氣管充氣征。 √肺血管淤血影：兩肺門血管影增多．兩肺或呈較粗網(wǎng)狀影。 √大量出血時(shí)兩肺透亮度明顯降低或呈“白肺 征。 J Pediatr 2022 Question ● Does prevention of patent ductus arteriosus reduce the incidence of pulmonary hemorrhage in preterm infant ? EBM – PICO P (population) – preterm infant I (intervention) – Indomethacin or ibuprofen C (pare) – placebo O (oute) – 1. patent ductus arteriosus
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