新生兒肺出血-lyjppt課件(已改無錯(cuò)字)
2023-02-19 22:06:12 本頁面
【正文】 Result of literature searching Prevention and 18 month Outes of Serious Pulmonary Hemorrhage in Extremely Low Birth Weight Infants: results from the trial of indomethacin prophylaxis in preterms (TIPP) Pediatrics 2022。 121(2), e233238 Intervention Indomethacin prophylaxis: (624hr) 2 trial: (Bandstra,Domancio) 1 trial: (TIPP) 1 trial: (Couser) Ibuprofen prophylaxis: (24hr) 10mg/kg ivd then 5mg/kg at 24, 48 hr Indomethacin prophylaxis ● Reduction of symptomatic PDA 。 RR: [,] RD: [,] NNT 4 ● Reduction of Gr 3 or 4 IVH [,] ● No significant reduction of PH RR= [,], RD [, ] ● No difference in mortality, RR= [ to ] ● Increase incidence of oliguria [,] Ibuprofen prophylaxis ● Significant reduced incidence of PDA [,], [,], NNT 3 ● Only 1 trial report incidence of PH (8% vs 3%) ● No difference in mortality, Gr 3/4 IVH, urine output ● One trial (Gournay 2022) stopped due to 3 cases severe pulmonary hypertension Definition of PH in in TIPP ● TIPP define PH as blo
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鄂ICP備17016276號-1