【正文】
Nikon, Tokyo, Japan). Viable cells stained only with AO were bright green with intact structure。LRRC4, a Putative Tumor Suppressor Gene, Requires a Functional Leucinerich Repeat Cassette Domain to Inhibit Proliferation of Glioma Cells In Vitro by Modulating theExtracellular Signalregulated Kinase/Protein Kinase B/Nuclear FactorκB PathwayMolecular Biology of the CellVol. 17, 3534–3542, August 2023Guiyuan Li et al. 0711078 曹廣超LRRC4 gene which contains a conserved leucinerich repeat (LRR) cassette and an immunoglobulin (Ig) IgC2 domain, is associated with glioma suppression both in vitro and in vivo. The present study provides evidence that the conspicuous absence of LRRC4 in highgrade gliomas directly cont