局部麻醉藥ppt課件(參考版)
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【正文】 Knowledge card ?Local anesthetics block the sodium channel in the nerve membrane. ?Adverse effects of the local anesthetics result from systemic absorption of toxic amounts of the drugs. ?Death can occur from respiratory failure secondary to medullary depression or from hypotention and cardiovascular collapse. summary 1. Local anesthetics prevent or relieve pain by interrupting nerve conduction. They bind to a specific receptor site within the pore of the Na+ channels in nerves and block ion movement through this pore. 2. The chemical and pharmacological properties of each drug determine its clinical use. Local anesthetics can be administered by a variety of routes, including topical, infiltration, field or nerve block, spinal, or epidural, as dictated by clinical circumstances. 3. Lidocaine also are properties of antiarrhythmic agents, discussed in Chapter 22. 4. surface anaesthesia—— tetracaine infiltration anaesthesia—— porcaine, lidcaine, etidocaine, ropivacaine, conduction anaesthesia—— li
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