【正文】
lar collapse. summary 1. Local anesthetics prevent or relieve pain by interrupting nerve conduction. They bind to a specific receptor site within the pore of the Na+ channels in nerves and block ion movement through this pore. 2. The chemical and pharmacological properties of each drug determine its clinical use. Local anesthetics can be administered by a variety of routes, including topical, infiltration, field or nerve block, spinal, or epidural, as dictated by clinical circumstances. 3. Lidocaine also are properties of antiarrhythmic agents, discussed in Chapter 22. 4. surface anaesthesia—— tetracaine infiltration anaesthesia—— porcaine, lidcaine, etidocaine, ropivacaine, conduction anaesthesia—— lidcaine, porcaine, bupivacaine , etidocaine spinal(subarachnoidal) anaesthesia—— lidcaine, tetracaine, porcaine epidural anaesthesia —— lidcaine, tetracaine, porcaine, bupivacaine ,ropivacaine, etidocaine 思考題 如何降低局麻藥的不良反應? 如何將局麻藥的影響因素與臨床應用相結合?