20xx年醫(yī)學(xué)專題—深度和節(jié)律的改變dyspneaonexertion勞力性呼吸困難orthopnea端-資料下載頁
2024-11-15 06:25本頁面
【正文】 at cardiomyocytes renew, with a gradual decrease from1% turning over annually at the age of 20 to 0.3% at the age of 75. Less than 50% of cardiomyocytes are exchanged during a normal lifespan. The capacity to generate cardiomyocytes in the adult human heart suggests that it may be rational to work towards the development of therapeutic strategies aiming to stimulate this process in cardiac pathologies.,were myocardial cells postmitotic cells?,Science 324: 98, 2009.,第三十五頁，共四十五頁。,Expounding 4：癥狀(zh232。ngzhu224。ng)和體征 signs and symptoms,Cardiac output ↓,Arterials perfusion ↓,Venous stagnation,renal,Fatigue Cardiac shock Sudden death,livergut lung skin,Edema Dyspnea Cyanosis,第三十六頁，共四十五頁。,Dyspnea 呼吸困難(hū xī k249。n n225。n),Respiratory become labored 呼吸費(fèi)力 Respiratory frequency depth and rhythm 呼吸頻率、深度和節(jié)律(ji233。lǜ)的改變,第三十七頁，共四十五頁。,Dyspnea on exertion 勞力(l225。ol236。)性呼吸困難 Orthopnea 端坐呼吸 Paroxysmal nocturnal dyspnea 夜間陣發(fā)性呼吸困難,Dyspnea 呼吸困難(hū xī k249。n n225。n),第三十八頁，共四十五頁。,? Fatigue ? Activities limited ? Chest congestion ? Edema or ankle swelling ? Shortness of breath,The Major signs and symptoms of CHF?,Think FACES.,疲乏 活動受限 胸悶 水腫或腳踝(jiǎo hu225。i)腫脹 氣促,第三十九頁，共四十五頁。,“Evolution” of Our Understanding of CHF 慢性(m224。n x236。ng)心衰的認(rèn)識演變,? cardiorenal model 心腎模型 Nawater retention ? Hemodynamic disorder 血流動力學(xué)紊亂(wěnlu224。n) reduced cardiac output and excessive vasoconstriction ? Neurohormonal model 神經(jīng)體液模型,第四十頁，共四十五頁。,Actin,myosin,troponin,Thick amp。 thin myofilament,105 ~ 107,Tropomyosin,,肌球蛋白 肌動蛋白 肌纖蛋白(d224。nb225。i) 肌凝蛋白 阻凝蛋白 親凝蛋白 原肌球蛋白 原肌凝蛋白 向肌球蛋白 Woe？！,第四十一頁，共四十五頁。,第四十二頁，共四十五頁。,第四十三頁，共四十五頁。,圖314 心臟(xīnz224。ng)反常收縮示意圖,正常(zh232。ngch225。ng)心臟 受損心臟變薄 室壓↑，膨突,第四十四頁，共四十五頁。,內(nèi)容(n232。ir243。ng)總結(jié),Heart Failure。心肌衰竭：原發(fā)性心肌病變，如心肌炎，心肌梗塞。自永嘉南渡，衣纓士人，多有遭者。風(fēng)毒中人，隨處皆得，作病何偏著于腳也。答曰∶夫人有五臟，心肺二臟，經(jīng)絡(luò)(jīnglu242。)所起在手十指。地之寒暑風(fēng)濕皆作蒸氣，足常履之，所以風(fēng)毒之中人也必先中腳。③心功下降，靜脈淤血，動脈缺血。Basic mechanisms,第四十五頁，共四十五頁
研究報(bào)告相關(guān)推薦
鄂ICP備17016276號-1