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20xx年醫(yī)學(xué)專題—第九章-白血病-資料下載頁

2024-11-13 12:09本頁面
  

【正文】 should be treated using leukapheresis ( exchanging transfusion) or preinduction treatment prior to intensive chemotherapy.,第五十七頁,共七十二頁。,Acute leukemia over 60 years of age is less responsive to chemotherapy. Standard twodrugs therapy can be used. CR 30% Intolerant to standard therapy. Lowdose of AraC can be used for 14~28 days.,第五十八頁,共七十二頁。,Therapy of the CNS leukemia,The CNS is a frequent sanctuary site for leukemic cells because most of the chemotherapy drugs are not able to reach the CNS. Some types of acute leukemia have tendency to be with CNS leukemia such as AML (M4, M5), ALL.,第五十九頁,共七十二頁。,Intrathecal chemotherapy,Cranial irradiation,第六十頁,共七十二頁。,Stem cell transplantations,The main purpose of BMT and PBSCT in cancer treatment is to make it possible for patients to receive very high doses of chemotherapy and/or radiation therapy. In addition, reestablished normal hematopoiesis and immune system by the healthy stem cells fight against leukemia effectively. So it change the vision in the medical history that leukemia is incurable malignancies.,第六十一頁,共七十二頁。,Three types of transplantation performed Allogeneic transplantation (HLAmatched individual donors) Syngeneic transplantation: identical twins. Autologous transplantation: patients receive their own stem cells,第六十二頁,共七十二頁。,Clinical results of stem cell transplantation,第六十三頁,共七十二頁。,Chronic myelogenous leukemia (CML),第六十四頁,共七十二頁。,第六十五頁,共七十二頁。,第六十六頁,共七十二頁。,第六十七頁,共七十二頁。,Future directions,第六十八頁,共七十二頁。,第六十九頁,共七十二頁。,第七十頁,共七十二頁。,復(fù)習(xí)(f249。x237。)思考題,1.慢性粒細(xì)胞白血病與類白血病反應(yīng)的鑒別要點(diǎn)? 2.白血病完全緩解的標(biāo)準(zhǔn)?為何要進(jìn)行鞏固、 強(qiáng)化化療? 3.骨髓增生異常(y236。ch225。ng)綜合征的分型、臨床表現(xiàn)、與急性 白血病的關(guān)系?,第七十一頁,共七十二頁。,內(nèi)容(n232。ir243。ng)總結(jié),第六篇 血液系統(tǒng)疾病。1.掌握急、慢性白血病的臨床表現(xiàn),實(shí)驗(yàn)室檢查及診斷標(biāo)準(zhǔn),治療原則。CD7(敏感),cCD3 (特異)。3.骨髓增生(zēngshēng)異常綜合征的分型、臨床表現(xiàn)、與急性。白血病的關(guān)系,第七十二頁,共七十二
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