【正文】
,Association between soluble CD40 ligand levels and the rate of cardiac events (death or nonfatal myocardial infarction) at 24 hours, 72 hours, 30 days, and 6 months among 544 patients receiving placebo.,Time,Death or Nonfatal Myocardial Infarction (%),24 hours,72 hours,30 hours,6 months,P=.13,P=.003,P=.004,P=.001,1st quartile 2nd quartile 3rd quartile 4th quartile 5th quartile,,,,,,,第十八頁,共二十二頁。,Clopidogrel, but not ASA, Reduces ADPInduced Expression of CD40L,Hermann A, et al. Platelets. 2001。12:7482. (with permission),第十九頁,共二十二頁。,Effect of Treatment with Abciximab According to the Levels of Troponin T and Soluble CD40 Ligand,Heeschen C, et al. N Eng J Med. 2003。348:11041111. (with permission),第二十頁,共二十二頁。,,Vascular Damage,Inflammation,Myocyte Necrosis,Accelerated Atherosclerosis,Hemodynamic Stress,HbA1c Blood glucose,CrCl Microalbuminuria,Troponin,BNP, NTproBNP,hsCRP, CD40L,Morrow DA, et al. Circulation. 2003。108:250252.,Multimarker Strategy in ACS,第二十一頁,共二十二頁。,內(nèi)容(n232。ir243。ng)總結(jié),Acute Coronary Syndromes Evaluation and Risk Stratification。Death/MI/RI。No. Studies: 13 6。CRP 210mg/l (n=294)。CRP 10mg/l (n=309)。CRP 2mg/l (n=314)。Chi Square: P=.0007。RcTnT(early +) AND。825 565 1133,第二十二頁,共二十二頁