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【正文】 esearch Objectives: Pathogenic Neisseria Section ? Investigates the Por B proteins of Neisseria gonorrhoeae and Neisseria meningitidis. ? Studies the natural epidemiology of Por variation using novel molecular typing methods ? Evaluates the effects of Por variation on hostpathogen interaction including immune responses to Por, structure function restrictions on Por, and transmission patterns ? Identifies the mechanisms of Por variation through investigation of mixed infections, diverse and clonal populations. Research Objectives: Lipopolysaccharide Section ? Conducts research to evaluate chemically or geically detoxified meningococcal LPS bound to protein as a potential vaccine for group B meningococcal disease. ? Studies the geics of LPS biosynthesis in pathogenic and mensal Neisseria species and characterizes their LPS immunochemically. Thank you
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