【正文】
ST Trial Primary Results PainFree SST研究為證實新檢測算法和出廠設置可以降低不恰當電擊率而設計 PainFree SST Trial Primary Results 27 主要目的 : 評估植入一年后 Medtronic Protecta DRICD/ CRTD 和 VRICD不恰當電擊率 Low Shock Rates in Patients with Dual and Triple Chamber ICDs Using Novel Detection Algorithms Study overview1 1. Auricchio 2022 Europace, 2. Heintze 2022 ACC poster, 3. Schloss 2022 HRS presentation PainFree SST Trial Primary Results 28 Inappropriate shock free rate at 1 year3 Enrollment Phase II (n=2536) Primary prevention (n=1826) Secondary prevention (n=710) Required programming PHD Follow up visit every 6mo April 2022 Enrollment Phase I (n=246) Inappropriate shock free rate at 1 year DRICD and CRTD (n=2022) VRICD (n=757) FU at 1, 3 and 6mo Safety and detection performance2 FU ≥ 1year (n=1308) FU 1year (n=699) Sep 2022 LBT EUROPACE 2022 階 段 I 階 段 II 一級終點:無不恰當電擊率 DR/CRTD: 一年 %患者 無不恰當電擊率 VR: 一年 %患者 無不恰當 Confidential and Proprietary。 Do Not Copy or Distribute 29 % (CI: % %) % (. % %) SmartShock? 在確保敏感性的同時顯著減少不恰當電擊的發(fā)生 1,2 1 Predicted from Virtual ICD: A Model to Evaluate Shock Reduction Strategies. Presented at HRS 2022 (P03125). 2 Protecta Clinical Study, Medtronic data on file. 3 Poole JE, Johnson GW, Hellkamp AS, et al. Prognostic importance of defibrillator shocks in patients with heart failure. N Engl J Med. September 4, 2022。359(10): Poster: Poole JE, et al. Analysis of ICD Shock Electrograms in the SCDHeFT Trial. Heart Rhythm Society Conference. 2022. 不必要 恰當 不恰當 美敦力減少電擊的完整管理方案 ATP During ChargingTM 優(yōu)化的 ATP無痛治療 Biv amp。 RV ATP ? Oversensing/Artifact T波識別 可程控的 RV感知環(huán)路 導線完整性報警 導線噪聲識別 智能電擊技術SmartShock 謝謝! 南方醫(yī)科大學 附屬南方醫(yī)院