【醫(yī)學課件】isis-4研究ppt課件-資料下載頁
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【正文】 rvival RESULTS continued 2P Dizziness With profound hypotension Renal dysfunction Mild Moderate Severe 110 () 30 () 170 () 74 () 23 () 13 () 155 () 83 () 316 () 130 () 68 () 26 () () () () () () () Other clinical events reported with captopril up to day 35 Placebo n=29,022 No. (%) Captopril n=29,028 No. (%) Excess/1000 (SD) ISIS4 Collaborative Group. Lancet 1995。 345: 669–85. ISIS4: Fourth International Study of Infarct Survival SUMMARY In patients with suspected or definite acute MI: ? Early treatment with captopril reduced allcause mortality at 35 days and during longterm follow up ? Mononitrate conferred no survival advantage in the short or long term ? Magnesium conferred no survival advantage, in contrast with earlier and smaller studies
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