【醫(yī)學(xué)課件】isis-2研究ppt課件-資料下載頁
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【正文】 ) SK better Placebo better Aspirin better Placebo better ISIS2: Second International Study of Infarct Survival RESULTS continued Reinfarction Major bleed (transfused) Minor bleed (not transfused) Stroke (excluding TIA) 202 18 81 67 238 46 297 61 284 33 163 81 156 31 215 47 123 11 33 45 77 24 167 25 Effects of SK and aspirin on clinical events The ISIS2 collaborative group. Lancet 1988。 ii: 349–60. Placebo infusion (n=8595) SK allocation Clinical event Placebo tablets (n=8600) SK (n=8592) Aspirin (n=8587) Both placebos (n=4300) SK and aspirin (n=4292) Aspirin allocation Combination therapy ISIS2: Second International Study of Infarct Survival SUMMARY Early therapy with SK and aspirin in patients with MI: ? Individually and in bination significantly reduced allcause mortality ? In bination demonstrated additive effect
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