【正文】
xtrans, HES ? Gelatins: prepared by hydrolysisof bovine collagen. monly available preparation succinylated gelatin (Gelofusin) ? Dextrans: highMW Dglucose polymers joined largely into linearbranched macromolecules ? HES: synthesized from amylopectin, a waxy starch derived from maize or shum Albumin and plasmaprotein fraction ? Human albumin: a naturally occuring monodiperse colloid ? FFP and plasmaprotein fraction: a more polydisperse humanderived colloidal solution with significant amounts of higherMW proteins globulins Blood Substitutes: hemoglobulin solutions ? At an early stage of development and probably some way from routine clinical use ? HBOC (Hemoglobicbased oxygencarrying pounds) ? PBOC (Perflourocarbonbased oxygencarrying pounds) ? Have a linear O2Hb dissociation profile and specific pharmacological effects Thank you for your attention !! Hemorrhagic shock Schematic diagram of capillary memebrane Crystalloids Colloids HES solutions HBOC