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ple supplying vessels. 第十八頁,共四十頁。 Pathological analysis ? The pathological diagnosis and categorisation of AAH, AIS, MIA and IAC were made based on the new pulmonary adenocarcinoma classification, 2024 edition . ? GGNs were resected by videoassisted thoracoscopy or thoracotomy surgery. ? All histological preparations and analyses were performed by two senior pathologists. In the case of disagreements, a consensus was reached after mutual discussion and/or consultation with a third pathologist. 第十九頁,共四十頁。 Statistical analysis ? SPSS for Windows, SPSS, Chicago, Ill ? Independent t test was used to pare different pathological groups (benign diseases, preinvasive diseases and invasive adenocarcinoma) of GGN. ? Correlations between pathological findings of GGNs and GGNvessel relationships were examined using Spearman’ s rank test. ? GGNvessel relationships between MIA and IAC diseases were pared using Pearson’ s chisquared test. ? When there was an expected value 1 or a pretest probability close to the test level, Fisher’ s exact test was used instead. Statistical results were considered significant when the P value was less than . 第二十頁,共四十頁。 Results Size variation of GGN lesions ? The average GGN size in the benign group, preinvasive group and adenocarcinomas group was 177。 mm, 177。 mm and 177。 mm, respectively. ? No significant differences existed between the preinvasive group and the benign group (t = ?,p=). ? However, there were significant differences between benign and preinvasive groups and the invasive adenocarcinoma group (t = ?,p=。 t = ?,p=). 第二十一頁,共四十頁。 Correlations between GGNvessel relationships and pathological findings ? Of 108 GGNs, type I, II, III and IV GGN vessell relationships were observed in 9, 58, 21 and 20 cases, respectively. ? the type II GGNvessel relationship was the dominant relationship in each pathological group, seen in 9 benign ( %), 16 preinvasive ( %) and 33 invasive ( %) GGN cases. 第二十二頁,共四十頁。 pared with the low incidence of type III and IV relationships in benign and preinvasive groups the bined incidence of type III ( %) and IV ( %) relationships in the invasive adenocarcinoma group reached %. 第二十三頁,共四十頁。 MIA could present four types, with type II as the major type ( %). The bination of type II and IV prised about 80 % of the MIA subgroup。 for IAC, type II and III had the same proportion of 40 %, hence the bination of 80 %. Statistical studies showed no difference in type II but a significant difference was found in type III and IV between MIA and IAC lesions (p =). 第二十四頁,共四十頁。 ? The vessel(s) traveling through GGN could be artery(ies) (category A), vein(s) (category B), or artery(ies) and vein(s)(category C). There were no significant differences and correlations between vascular categories and GGN groups(p = and , respectively) . 第二十五頁,共四十頁。 A further examination of the correlation between vascular categories and GGNs with type III and IV relationships did not generate any significant results (p =). 第二十六頁,共四十頁。 Discussion ? Solitary pulmonary nodules (SPNs) are mon findings in ? CT examinations and can be divided into two groups based ? on density variation: solid nodules and GGNs. ? In 2024, the International Association for the Study of Lung Cancer, the American Thoracic Society and the Eur