【正文】
food production can be happily seen at global agricultural 1983 when the first time human got transgenic tobacco, potato by using rebinant DNA technology,the plant geic engineering technology in the world has achieved rapid development of transgenic plants for research and development,which has made a series of remarkable progress and has Successfully nurtured a number of crops with diseaseresistance,insecticide resistance and even an incredible the help of them,we can feed another more than millions of people,According to statistics,up to now ,no less than billion people have benefits from the area,our mother country China has made tremendous contributions to the world39。s must be mentioned is BT cotton and hybrid rice of Yuan Longping. Commercialize geically modified crops dates from the year of 1996,including Soybeans, cotton, cereals and oilseed crops now occupy 10% of global arable land. In 2020,81% of worldwide soybean, 64% cotton, 29% and 23% of the grain is geically modified oilseed ,29 countries grow GM products all over the top three country with the largest area of cultivation is United States, Brazil and problem About the safety of GM products has been modified food will bring human and animal allergens and toxins of unknown. 3 Chapter 3 GM food safety issues International consensus has been reached on the principles regarding evaluation of the food safety of geically modified plants. The concept of substantial equivalence has been developed as part of a safety evaluation framework, based on the idea that existing foods can serve as a basis for paring the properties of geically modified foods with the appropriate counterpart. Application of the concept is not a safety assessment per se, but helps to identify similarities and differences between the existing food and the new product, which are then subject to further toxicological investigation. Substantial equivalence is a starting point in the safety evaluation, rather than an endpoint of the assessment. Consensus on practical application of the principle should be further elaborated. Experiences with the safety testing of newly inserted proteins and of whole geically modified foods are reviewed, and limitations of current test methodologies are discussed. The development and validation of new profiling methods such as DNA microarray technology, proteomics, and metabolomics for the identification and characterization of unintended effects, which may occur as a result of the geic modification, is remended. The assessment of the allergenicity of newly inserted proteins and of marker genes is discussed. An issue that will gain importance in the near future is that of postmarketing surveillance of the foods derived from geically modified crops. It is concluded, among others that, that application of the principle of substantial equivalence has proven adequate, and that no alternative adequate safety assessment strategies