【正文】
都明顯擴(kuò)張,從妊娠期的前 3個(gè)月開始出現(xiàn),產(chǎn)后 3- 4個(gè)月逐漸恢復(fù)。 妊娠時(shí)腎臟改變 ?腎臟體積和重量增加:由于腎臟血流增加、血管間質(zhì)容量增加。單純水腫多是良性的,同新生兒圍產(chǎn)期死亡率無相關(guān)性。中山大學(xué)附一院腎內(nèi)科 陳崴 妊娠與腎臟病 CASE A 32yearold white woman is admitted with headache and hypertension at 22 weeks gestation. During the current pregnancy, her BP was 110/80 at 7 weeks gestation, but increased to 130/80 at 9 weeks and 140/90 at 19 weeks. Her past history is positive for two previous spontaneous abortions at 11 and 12 weeks gestation. Physical examination reveals BP of 150/110, both pulmonary congestion and peripheral edema, and hyperreflexia with 3 to 4 beat clonus. LABORATORY DATA ?BUN Creatinine 88μ mol/L ?Hematocrit 28 % Hgb 9g/L Ret 2% ?Platelets 61,000 ?PT,APTT normal C3 (normal equals ) ALT,AST,GGT increased Uric acid 321 μ mol/L ?ACL + ?Three days later, the patient had blurred vision and nausea。 she had a grand mal seizure in the emergency room. At this time her BP is 205/130, retinal hemorrhages and papilledema are noted, and the patient is hyperreflexic. Her blood pressure is very difficult to control ? ? ? ? 診斷 ?The patient is diagnosed as having eclampsia with the HELLP syndrome and pregnancy is terminated. ?(HELLP = hemolysis, ele