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中腦導(dǎo)水管周圍灰質(zhì)在痛覺調(diào)制中的作用-資料下載頁

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【正文】 modulation. Brain Res Bull, 1994,34:57558515. 管振龍, 張文斌, 、中縫背核、, 1997,13(4): 397404,1984,15:294300.,2000,6(2):104108,(醫(yī)學(xué)版), 2002,23(4):329332 M V: Immunoreactive βendorphin and ACTH in the same neurons of the hypothalamic arcuate nucleus in the rat. Am J Anat 1997,154:283 B M. Anatomy and physiology of the neuroendocrine arcuate nucleus. Peptides 1985,6(suppl 2): 1 M J, Gramsch C, Przewtochi R, et al: Lesions of the hypothalamic arcuate nucleus produce a temporary hyperalgesia and attenuate stressevoked analgesia. Life Sic 1980,27:1513—,1986,17:386393—,1987,18:148152,20:1599,. 生理學(xué)報(bào), 1994,46(4):320326,1995,47,(3):29229627. Willis WD, Westlund KN. Neuroanatomy of the pain system and of the pathways that modulate pain. J Clin Neurophsiol,1997,14∶231,Gebhart :,1993,24:252254 AA, Chang MH, Zhuo M. Spinal serotonergic receptors mediate facilitation of a nociceptive reflex by subcutaneous formalin injection into the hindpaw in rats. Brain Res, 1998,798:4654,1997,103118.31. 11 Urban MO, Gebhart GF.Characterization of biphasic modulation of spinal nociceptive by neurotensin in the rat rostral ventromedial medalla.J Neurophysiol,1997, 78:15501562 M, et al: The regulation and function of cfos and other immediate early gene in the nervous system. Neuron, 1990,4:477485 JD, et al: Differential regulation of neuropeptide and prooncogene mRNA content in the nervous system. Neuron 1990,4:477485 K, et al: Preproenkephalin mRNA in spinal dorsal horn neurons is induced by peripheral inflammation and is colocalized with Fos and Fosrelated proteins. Neuroscience 1992 46(3): 561570,周敬修,1995,22(1):1923, 凌樹才, , 2004,27(5): 514517, , 2004,37(6): 50450612內(nèi)容總結(jié)(1)中腦導(dǎo)水管周圍灰質(zhì)在痛覺調(diào)制中的作用
中腦導(dǎo)水管周圍灰質(zhì)(periaqueductal gray, PAG)是位于中腦頂蓋與被蓋之間由一群小而高密度的神經(jīng)細(xì)胞圍繞中腦水管構(gòu)成的一片環(huán)形區(qū)域,其頭側(cè)達(dá)后連合水平,與第三腦室的室周灰質(zhì)相續(xù)(2)腦干的下行抑制及易化系統(tǒng)是同時(shí)被激活的,當(dāng)下行抑制及易化調(diào)節(jié)系統(tǒng)的失衡并引起內(nèi)源性易化系統(tǒng)的效應(yīng)增高時(shí),非傷害性刺激也可被感覺為疼痛
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