合成肽s247-預(yù)先給藥對(duì)大鼠呼吸機(jī)相關(guān)性肺損傷的影響-資料下載頁(yè)
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【正文】 critical mediator of acute lung injury[J] . J Clin Invest , 2001 , 107(12):15371544 .[3] 王月蘭 , 姚尚龍 . 絲裂原蛋白激酶信號(hào)轉(zhuǎn)導(dǎo)通路在機(jī)械通氣相關(guān)性肺損傷中的作用[J] . 中華實(shí)驗(yàn)外科雜志 , 2006 , 23(3):331333 .[4] KWONG KY , LITERAT A , ZHU NL , et al . Expression of transforming growth factor beta (TGFbeta1) in human epithelial alveolar cells: a proinflammatory mediator independent pathway[J] . Life Sci , 2004 , 74(24):29412957 . [5] BELLOCQ A , AZOULAY E , MARULLO S , ea al . Reactive oxygen and nitrogen intermediates increase transforming growth factorbeta1 release from human epithelial alveolar cells through two different mechanisms[J] . Am J Respir Cell Mol Biol , 1999 , 21(1):128136 .[6] DAS KC , LEWISMOLOCK Y , WHITE CW , et al . Activation of NFkappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells[J] . Am J Physiol , 1995 , 269(5 pt 1):L588L602 . [7] SHEPPARD D. Integrinmediated activation of transforming growth factorbeta(1) in pulmonary fibrosis[J] . Chest , 2001 , 120(1 Suppl):49S53S.[8] MU D , CAMBIER S , FJELLBIRKELAND L , et al . The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1MMPdependent activation of TGFbeta1[J] . J Cell Biol , 2002 , 157(3):493507 .[9] SHANNON KE , KEENE JL , SETTLE SL , et al . Antimetastatic properties of RGDpeptidomimetic agents S137 and S247[J] . Clin Exp Metastasis , 2004 , 21(2):129138 .內(nèi)容總結(jié)
（1）合成肽S247預(yù)先給藥對(duì)大鼠呼吸機(jī)相關(guān)性肺損傷的影響作者單位：430022 武漢，華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院麻醉科
華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院麻醉科，武漢 430022
桂平 武慶平 姚尚龍
【摘要】 目的 研究合成肽S247預(yù)先給藥對(duì)大鼠呼吸機(jī)相關(guān)性肺損傷（VILI）的影響及其機(jī)制
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