免疫球蛋白４-資料下載頁
2025-09-25 17:10本頁面
【正文】 concepts ? Multiple V genes ? VJ and VDJ joining ? Junctional diversity ? N region insertions ? Somatic mutation ? Combinatorial association ? Multispecificity Generation of Diversity B ce ll r e c e p tor (I mmu n o g lob u li n ) H e a v y L igh t V ge n e se g me n ts 1000 300 D ge n e se g me n ts 15 J ge n e se g me n ts 4 4 N r e g ion i n s e rt ion ++ J u n c ti o n a l d iv e rsit y +++ + S o ma ti c mutat ion + + V x D x J 1 0 0 0 x 15 x 4 V x J 3 0 0 x 4 T o tal 6 x 104 1 .2 x 103 C o mb ina tori a l a s s o c iati o n 7 .2 x 107 ? Ag independent process ? Clonal selection T Cell Antigen Receptor ? Heterodimer of an ? and a ? chain ? Gene structure and expression of the ? chain is analogous to the immunoglobulin heavy chain ? Gene structure and expression of the ? chain is analogous to the immunoglobulin light chain ? No somatic mutation in T cells
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鄂ICP備17016276號-1