蛋白質分子設計ppt課件(2)-資料下載頁
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【正文】 a 3D structure profile Schematic description of the construction of a 3D structure profile 3D structure profile Zscore There are 18 kinds of environment classes The environment of a side chain is first classed as buried, partially buried, or exposed according to its solventaccessible surface area. The buried and partially buried residue environments are further subdivided based on the fraction of the sidechain area that is covered by polar atoms. There are 18 kinds of environment classes The buried class is subdivided into three classes, labeled B1, B2, and B3 in order of increasing environmental polarity. Similarly, the residue positions in the partially buried class are subdivided into two types, labeled P1 and P2 in order of increasing polarity. There are 18 kinds of environment classes The exposed sidechain category, labeled E, is not subdivided into polarity classes, because we treat water as polar, and exposed positions are necessarily in a polar environment. There are 18 kinds of environment classes To account for the slight preferences of certain residue types to be in particular secondary structures, residues in the sidechain environment classes are further distributed into three secondary structure types, ? helix, ? sheet, and other, to give a total of 18 environment classes. 114 The 3D1D scoring table (Proteins (1991), 10:229) An example of 3D profile Science (1991), 253:164170111111111 44487? 1 ? 2 過眼云煙 ? 3 古古怪怪 ? 4 ? 5 ? 6男 ? 7古古怪 ? 8vvvvvvv ? 9方法 ?? 古古廣告和叫姐姐 ? 和呵呵呵呵呵斤斤計較斤斤計較 ? 化工古怪怪古古怪怪個 ? Ccggffghfhhhf ? Ghhhhhhhhhh ? 1111111111 ? 2222222222 ? 555555555 ? 8887933 ? Hhjjkkk ? 瀏覽量瀏覽量了 ? ? ? 111111111111 ? 000?56666666666666666655555555555555555556558888 ?Hhuyuyyutytytytyyuuuuuu ? ? ?455555555555555 ?4555555555555555 ?發(fā)呆的叮當當的的 ??5466666666 ?54444444444 ?風光好 ? ? ? ? 方官方共和國 ? hggghgh554545454?11111111111122222222 ?盡快快快快快快快家斤斤計較斤斤計較計較環(huán)境及斤斤計較斤斤計 ?? 4444444 ? 777 ? 44444011011112 ? 古古怪怪 ? 4444444444444 ? 555 ? 444444444? 54545454 ? 哥 vnv ? ? 合格和韓國國 ? 版本 vnbngnvg ? 和環(huán)境和換機及環(huán)境和交換機 ?? 11111 ? 該放放放風放放風方法 ? ? 諤諤看看 ? ??快盡快盡快盡快將見快盡快盡快盡快將盡快空間進間 ?空間接口可看見看見 ?? 455454545445 ? Hkjjkhh ? ? 嘎嘎嘎 ? 你 ? ? ?? 12222222222223211 ? 21111122222222222 ?? 快快快快快殲擊機 ? 斤斤計較就就 ? ? ? 444444444444444 ? ? ? hhhjkjkj ??呵呵呵呵呵呵哈 ? ?嘎嘎嘎 ? 44444888 ?的瑣瑣碎碎 ?? 嘎嘎嘎 ? 放放風 ? 嘎嘎嘎 ? ? ? 嘎嘎嘎嘎嘎嘎搞個
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