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to the title conclusion.第六 頁(yè) ,共二十一 頁(yè) 。 ENIs early EN superior to delayed EN? There are no data support using early EN can improve their prognosis, but the mittee still remend the early(24h) appropriate amount of feeding (C). a. meta analysis and systematic review A meta analysis of 15 RCTs (surgery, trauma, head injury, burns or suffering from acute medical conditions), showed early EN can reduce the infectious plications and length of stay. systematic review of 19 studies can show early EN play a positive effect on the survival rate、 length of treatment, the rate of septic. and other plications, the conclusion provide 1 level evidence for using the early EN. b. Individual studies: (remendation level C) Moore and Jones Graham和 coworkers Chiarelli et al Eyer et al Hasse et al Singh et al第七 頁(yè) ,共二十一 頁(yè) 。No general amount remend to be adjust EN therapy according to courseof disease. But exogenous energy supply of the acute and initial phase:≤25kcal/kg/d and recovery: ≥25kcal/kg/d may be favourable (C)a. Prospective observational cohort studyb. Ibrahimc. A recent trial ENhow much?第八 頁(yè) ,共二十一 頁(yè) 。 which route ?167。 Jejunal versus gastric feeding in critically illness patient is no difference (C).167。 Jejunal feeding apply to patient post abdominal trauma or elective abdominal surgery or intolerance to gastric feeding randomised trials第九 頁(yè) ,共二十一 頁(yè) 。 Is a peptidebased formula preferable to a whole protein formula?167。 Whole protein formulae are appropriate in most patients( C)167。 Exocrine pancreatic function is reduced in sepsis, the digestion and absorption of whole protein formulae should be concerned. a. four randomised trials.第十 頁(yè) ,共二十一 頁(yè) 。 When should motility agents be used in critically ill patients?If the patient intolerance (such as high gastric residuals) to EN, metoclopramid(胃復(fù)安) or Erythromycin(紅霉素) should be considered , . with highgastric residuals (C).a. Booth( Metaa