氰轉(zhuǎn)化為酰胺(編輯修改稿)
2025-09-01 08:19 本頁面
【文章內(nèi)容簡介】 a with the speed that keep the temperature less than 50℃. The precipitated ammonium sulphate was filtered off, and the filtrate was cooled. The precipitate was collected by filtration, and the filter cake was washed by water, dried in vacuum to give the desired product. H2O2K2CO3DMSO體系水解腈為伯酰胺示例[1]To a stirred solution of 4chlorobenzonitrile ( g, mol) in DMSO (3 ml), cooled in a ice bath, was added 30% H2O2 ( ml) and K2CO3, the reaction was allowed to warm up to . (strong exothermic effect was observed). After 5 min., distilled water (50 ml) was added, cooling applied, and the product was collected by filtration, yield 85%. NaOH(aq.)CH2Cl2相轉(zhuǎn)移催化體系水解腈為伯酰胺[2]To a magnetically stirred dichloromethane solution ( ml) of otolunitrile ( g, mmol) cooled in an ice bath, are added 30% hydrogen peroxide ( ml), tetrabutylammonium hydrogen sulfate ( g, mmol), and a 20% aqueous solution of sodium hydroxide ( ml). The reaction mixture is allowed to warm up to . and maintained under stirring. After h, dichloromethane is added, the or
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