發(fā)育生物學(xué)文獻(xiàn)閱讀(編輯修改稿)
2025-02-14 01:16 本頁(yè)面
【文章內(nèi)容簡(jiǎn)介】 ion, smallRNA–based mechanisms monitor and enforce gametic genome integrity, which is required for successful fertilization. 在準(zhǔn)備期，小分子 RNAs為基礎(chǔ)的機(jī)制監(jiān)控和促使果蠅配偶子基因完整，這是成功繁殖的前提。 the female germline itself, posed of the haploid oocyte and polyploid nurse cells, faces the threat of many endogenous transposon types. →Small RNAs 雌種系本身由雙倍體卵母細(xì)胞和多倍體培育細(xì)胞組成，面臨著許多內(nèi)生的轉(zhuǎn)座子的脅迫， so， SmallRNAs作用 In the embryo, these paternal 21nt siRNAs could degrade（降低） transposon RNAs that have potentially escaped TGS This process could, in principle, unfavorably silence master pingpong piRNA clusters (., 42AB) and ultimately promise the pathway’ s adaptive potential, but a distinct HP1 homolog, Rhino, apparently prevents this by peting with HP1α at the 42AB locus 即：調(diào)控基因表達(dá)，形成 what The system fails, however, if paternal transposons are too sequencedivergent to be recognized by the maternal piRNA reservoir (Fig. 4A). This incurs “ hy
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