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the ratio of the relative value of making the mR. Take control of the relative expression for 1, each of the relative amount pared with the expression with multiple of said.1. 2. 3 pp38 protein expression detection with 100 ng/ml Ghrelin pretreatment cell 1 h joined after 10 ng/ml of TNF alpha, cultivate 30 min respectively, collect cells, extraction protein, immune imprinting method to detect pp38, beta actin expression. With pp38 and beta actin density of the ratio of the said purpose the relative content of protein, the relative expression for the control group of 1, each of the relative amount pared with the expression with multiple of said.1. 2. 4 statistical methods using SPSS 13. 0 software parison between groups, measurement data with 珋 x 177。 s said, pares the two two LSD method. With P than 0. 05 for statistically significant.2 the results2. 1 MCP1 mRNA without the express HBMEC cells stimulate MCP1 mRNA expression level is low, TNF alpha stimulation, MCP1 express obvious enhancement, the concentration of a certain doseresponse relationship (P 0. 05), see figure 1. Ghrelin alone to MCP1 role to express the impact is not big, but Ghrelin pretreatment can reduce TNF alpha induction of MCP1 mRNA expression (P 0. 05), see figure 2.2. 2 pp38 Ghrelin protein expression of TNF alpha induction of cytoplasmic pp38 protein expression influence the results shown in figure 3. The figure 3 shows, normally, HBMEC cytoplasmic express certain pp38 protein that TNF alpha stimulate 30 min, the cytoplasmic pp38 protein significantly increased, and Ghrelin separate function group pp38 protein expression the normal group is less。 Ghrelin pretreatment group in the cytoplasm pp38 protein is TNF alpha group reduce (p 0. 05).3 discussThere is evidence that the metabolic syndrome in express MCP1, TNF alpha channel have special role. To determine whethe