【文章內(nèi)容簡介】
um iodide and immunofluorescent double staining through flow cytometry were utilized to explore cell cycle distributions and the expression of CD34 and Ki67, the cell proliferationrelated protein in bone marrow mononuclear . Compared with the control group, the percentages of G0/G1 phase of cell cycle, haemopoietic stem/progenitor cells CD34+ cells, Ki67+ cells, CD34+Ki67+ cells, Ki67+ cells in CD34+ cells, and CD34+ cells in Ki67+ cells of BMMNC were all significantly increased in the MDS and AL group (). The percentages of Ki67+ cells in CD34+ cells was significantly lower (P), as well as the percentages of CD34+ cells, CD34+Ki67+ cells, and CD34+ cells in Ki67+ cells of BMMNC were all significantly lower in the AA group than those in the control group (P).4. The percentages of G0/G1 phase, CD34+, Ki67+, CD34+Ki67+, Ki67+ cells in CD34+, and CD34+ cells in Ki67+ cells were all significantly increased (P), although the proportions of S and S+G2/M phases were both significantly decreased in the RA group than the AA group (P).CONCLUSIONS1. Most of the cells are kept at the G1 phase as well as the high proliferation of the haemopoietic stem/p