哈爾濱醫(yī)科大學醫(yī)學微生物學致病性細菌腸道感染病毒(編輯修改稿)
2025-02-09 16:45 本頁面
【文章內容簡介】 ic polio (major illness), % ? asymetric flaccid paralysis / paresis. Lower, or upper extremities ? Postpolio syndrome ? progressive atrophy years later Department of Microbiology, Harbin Medical University Department of Microbiology, Harbin Medical University 免疫性 ?牢固特異免疫， 體液免疫為主 ?腸道局部 sIgA ?血液中和性 IgG、 IgM抗體 ?中和抗體可長時間維持（終生） ? 3型間交叉保護極弱 Department of Microbiology, Harbin Medical University Laboratory Diagnosis ? Virus Isolation ? Serology Department of Microbiology, Harbin Medical University 預防原則 ?流行期不宜做小兒扁挑體摘除術和其他疫苗接種 ?疫苗接種：最好的手段 ?被動免疫：易感者用丙種球蛋白 Current Status of Wild Poliovirus Transmission Department of Microbiology, Harbin Medical University ?我國政府規(guī)定每年 12月 5日和 1月 5日為脊灰疫苗日。 Department of Microbiology, Harbin Medical University 柯薩奇病毒（ Coxsackievirus） ? 1948年美國紐約州 Coxsackie鎮(zhèn) ?一名疑似脊髓灰質炎的患兒糞便中用乳鼠接種的方法分離發(fā)現(xiàn) Department of Microbiology, Harbin Medical University Groups ? Group A viruses (23 types) ? Group B viruses (6 types) ?Distinguished from other enteroviruses by their pathogenicity for suckling mice ?Group based on the lesions in suckling mice. Department of Microbiology, Harbin Medical University Pathogenesis ? FecalOral route trasmission ? Spread in the body like polioviruses Department of Microbiology, Harbin Medical University Department of Microbiology, Harbin Medical University Department of Microbiology, Harbin Medical University Department of Microbiology, Harbin Medical University Disease Associations ? Paralytic Disease ? Meningitis ? Encephaliti
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