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脂肪酸的代謝ppt課件(編輯修改稿)

2025-01-31 20:50 本頁面
 

【文章內(nèi)容簡介】 ents phosphatidylglycerol。 PS, phosphatidylserine. Origin of the polar head groups of phospholipids in E. coli These glycerophospholipids are synthesized using strategy 1. Phosphatidylglycerol is synthesized as in bacteria. PI represents phosphatidylinositol. Synthesis of cardiolipin and phosphatidylinositol in eukaryotes The “salvage” pathway from phosphatidylserine to phosphatidylethanolamine and phosphatidylcholine in yeast. Phosphatidylserine and phosphatidylethanolamine are interconverted by a reversible headgroup exchange reaction. In mammals, phosphatidylserine is derived from phosphatidylethanolamine by a reversal of this reaction。 adoMet is Sadenosylmethionine。 adoHcy, Sadenosylhomocysteine. Pathway for phosphatidylcholine synthesis from choline in mammals. The same strategy shown here (strategy 2) is also used for salvaging ethanolamine in phosphatidylethanolamine synthesis. Summary of the pathways to phosphatidylcholine and Phosphatidylethanolamine. Conversion of phosphatidylethanolamine to phosphatidylcholine in mammals takes place only in the liver. 真核細胞中磷脂的合成(綜合 1 ) 真核細胞中磷脂的合成(綜合 2) 哺乳動物磷脂酰膽堿和磷脂酰乙醇氨的相互轉(zhuǎn)化 真核細胞中 CDP二酰甘油是合成磷脂酰肌醇,磷脂酰甘油,心磷脂的前體。 血小板活化因子 :1烷基 2乙酰甘油磷酸膽堿的合成 物合成由 3酮鞘氨醇合成酶催化的反應(yīng)開始 3酮鞘氨醇 二氫鞘氨醇 N脂酰二氫鞘氨醇 神經(jīng)酰胺 動物細胞中糖基神經(jīng)酰胺,神經(jīng)節(jié)苷脂和鞘磷脂的由神經(jīng)酰胺合成。 鞘磷脂 合成前列腺素,血拴烷和白三烯的前體。 前列腺素內(nèi)過氧化物合成酶催化PGH2的合成 阿斯匹林使環(huán)加氧酶失活 甲羥戊酸的合成 甲羥戊酸合成的機制 HMGCoA還原酶的活力受合成速度、降解速度及磷酸化和脫磷酸調(diào)控。 甲羥戊酸到鯊烯的轉(zhuǎn)化 Oxidation at C15 converts retinol to the aldehyde, retinal (c), and further oxidation produces retinoic acid (d), a hormone that regulates gene expression. Retinal bines with the protein opsin to form rhodopsin (not shown), a visual pigment widespread in nature. In the dark, retinal of rhodopsin is in the 11cis fo
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