20xx年醫(yī)學(xué)專題—pantoprazole-sodium-中國(guó)藥典標(biāo)準(zhǔn)翻譯-全文預(yù)覽
【正文】 en the sample with a small amount (usually ~) of sulfuric acid, then heat gently at a temperature as low as practicable until the steam of sulfuric acid is wiped off, add of nitric acid, keep heating until the fumes are no longer evolved, then ignite at 500~600℃ until the residue is pletely incinerated, cool the crucible. The test is carried out according to Appendix Ⅷ H Method Two, starts from “add 2ml of hydrochloric acid〞. The heavy metals should not be more than 20ppm.[Content Determination] Carry out the method for high performance liquid chromatography (Appendix Ⅴ D). Chromatographic conditions and system suitability The column is packed with octadecyl silane bonded silica gel。 detection wavelength is 289 nm。Pantoprazole SodiumC16H14F2N3NaO4S any colour produced is not more intense than that of reference solution Y2 (Appendix Ⅸ A, method 1). Related substances Dissolve a quantity of the product in solvent [ mol/L sodium hydroxideacetonitrile (1:1)] to obtain a solution of mg per ml as test solution. Pipet accurately 1 ml of the test solution, to a 100 ml volumetric flask, dilute to volume with above solvent, mix well as reference solution. Carry out the method for hig
環(huán)評(píng)公示相關(guān)推薦
鄂ICP備17016276號(hào)-1