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的。 M. Cortey 來自 加泰羅尼亞 政府, T. Kekarainen 由西班牙政府支持 參考 Bendinelli, M., Pistello, M., Maggi, F., Fornal, C., Freer, G., Vatteroni, L., 2021. Molecular properties, biology and clinical implications of TT virus, a recentlyidentified widespread infectious agent of humans. Clin. Microb. Rev. 14, 98113. Biagini, P., 2021. Classification of TTV and Related Viruses (Anelloviruses), in: de Villiers, ., zur Hausen, H. (Eds.), TT Viruses. The Still Elusive Human Pathogens. SpringerVerlag, Berlin, pp. 2134. Biagini, P., Uch, R., Belhouchet, M., Attoui, H., Cantaloube, ., Brisbarre, N., de Micco, P., 2021. Circular genomes related to anelloviruses identified in humanand animal samples by using a bined rollingcircle amplification/sequence304 independent single primer amplification approach. J. Gen. Virol. 88, 2696– 2701. Bigarr233。ria de la UAB, 157 pp. PhD dissertation. Hall, ., 1999. BioEdit: a userfriendly biological sequence alignment editor andanalysis program for Windows 95/98/NT. Nuc. Ac. Symp. Ser. 41, 9598. Huang, ., Ni, ., Dryman, ., Meng, ., 2021. Multiple infection of porcine Torque teno virus in a single pig and characterization of the fulllength genomicsequences of four . prototype PTTV strains: Implication for genotyping of PTTV. Virol. 396, 289– 297. Jelcic, I., HotzWagenblatt, A., Hunziker, A., zur Hausen, H., de Villiers, ., 2021. Isolation of Multiple TT Virus Genotypes from Spleen Biopsy Tissue from a Hodgkin’s Disease Patient: Genome Reanization and Diversity in the Hypervariable Region. J. Virol. 78, 7498– 7507. Kakkola, L., Hedman, J., Qiu, J. amp。nez, L., Kekarainen, T., Sibila, M., RuizFons, F., Vidal, D., Gort225。 圖 2成對的核苷酸序列比較序列分布在 23個(gè) TTSuV 基因組: 1,觀察內(nèi) TTSuV1和 TTSuV2 差異 。 表 1。 表 3。在檢測到變異病毒基因組豬圓環(huán)病毒組能提升在未翻譯地區(qū) (非編碼區(qū))和預(yù)測的開放閱讀框( ORF)。 圖 3 鄰 joining 進(jìn)化樹的基礎(chǔ)上, TTSuV 百分比的身份,在基因銀行中的基因組可從這項(xiàng)研究。s, J., 2021. Torque teno virus (TTV) is highly prevalent in the European wild boar (Sus scrofa). Vet. Microbiol. 118, 223229. McKeown, ., Fenaux, M., Halbur, ., Meng, ., 2021. Molecular characterization of porcine TT virus, an orphan virus, in pigs from six different countries. Vet. Microbiol. 104, 113117. Nei, M., Kumar, S., 2021. Molecular Evolution and Phylogeics, first ed. Oxford University Press, New York. Nei, M., Gojobori, T., 1986. Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol. Biol. Evol. 3, 418426. Ng, ., Suedmeyer, W. K., Wheeler, E., Gulland, F., Breitbart, M., 2021. Novel anellovirus discovered from a mortality event of captive California sea lions. J. Gen. Virol. 90, 1256– 1261. Niel, C., DinizMendes, L., Devalle, S., 2021. Rollingcircle amplification of Torque tenovirus (TTV) plete genomes from human and swine sera and identification of a novel swine TTV genogroup. J. Gen. Virol. 88, 13431347. Okamoto, H., 2021. TT Viruses in Animals, in: de Villiers, ., zur Hausen, H. (Eds.), TT Viruses. The Still Elusive Human Pathogens. SpringerVerlag, Berlin, pp. 35 52. Okamoto, H., Nishizawa, T., Takahashi, M., Tawara, A., Peng, Y., Kishimoto J., Wang, Y., 2021. Genomic and evolutionary characterization of TT virus (TTV) in tupaias and parison with speciesspecific TTVs in humans and nonhuman primates. J. Gen. Virol. 82, 20412050. Okamoto, H., Takahashi, M., Nishizawa, T., Tawara, A., Fukai, K., Muramatsu, U., Naito, Y., Yoshikawa, A., 2021. Genomic characterization of TT viruses (TTVs) in pigs, cats and dogs and their relatedness with speciesspecific TTVs in primates a