侵襲性深部真菌病的實(shí)驗(yàn)室診斷-在線瀏覽
2025-02-23 21:57本頁面
【正文】 ncidence of IFD correlated directly and significantly (x2 p=) with risk stratification group: highest proportion in the highrisk group. Since all the biomarkers have inherent limitations, a better diagnosis yield is achieved bining the biomarkers. All three biomarkers share high negative predictive value and can exclude reasonably IFD in haematology adult patients treated with wide spectrum antifungals. Evaluation of two serologic test for diagnosis invasive Aspergillosis C. Castro, A. Romero, A. Aller, T. Gonzalez, A. Gonz225。nMazuelos H. U. Valme, SEVILLA, Spain ?A total of 236 sera from 51 patients in risk of IA were tested for GM using Platelia Aspergillus kit (Bio Rad, France) which 36 sera (10 patients) were tested for BG also using Fungitell kit (Associates of Cape Cod., USA). ?Patients were attended at the University Hospital of Valme from Seville from January of 2023 to December 2023. ?Patients with GM index ≥ in two consecutive samples have been marked as GM positive and samples with results ≥80pg/ml were marked as BG positive. All GM positive patients were classified according to EORTC/MSG criteria (2023) for probability of IA. GM test ? From 51 patient studied, 16 of them showed at least one positive specimen (33 sera). ? Only 6 patients showed two consecutive positive results (≥ GM test) and they show clinical signs or microbiological criteria for AI proven (3 patients) and probable (3 patients). BG assay ? The BG assay were used in parallel with GM in 36 sera which 26 showed positive result from 9 patients, (3 with AI proven and 6 AI probable). ? 3 patients showed positive results before for
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