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9。Copyright 169。 2022 Pearson Education, Inc. publishing as Benjamin Cummings Anticipatory Questions ? 1. What might happen if an anism had its cells expressing all genes within the genome all the time? ? 2. At what levels can control of cellular activities/pathways be controlled? ? 3. Based on our discussions up to this point, what do you think the term “negative feedback” means? ? 4. What steps are involved in the initiation of prokaryotic transcription? Copyright 169。 2022 Pearson Education, Inc. publishing as Benjamin Cummings Individual bacteria respond to environmental change by regulating their gene expression ? A bacterium can tune its metabolism to the changing environment and food sources ? This metabolic control occurs on two levels: – Adjusting activity of metabolic enzymes – Regulating genes that encode metabolic enzymes LE 1820 Regulation of enzyme activity Regulation of enzyme production Enzyme 1 Regulation of gene expression Enzyme 2 Enzyme 3 Enzyme 4 Enzyme 5 Gene 2 Gene 1 Gene 3 Gene 4 Gene 5 Tryptophan Precursor Feedback inhibition Copyright 169。 2022 Pearson Education, Inc. publishing as Benjamin Cummings Trp Operon Animation ? 3/ Copyright 169。 binding of a repressor to the operator shuts off transcription ? The trp operon is a repressible operon ? An inducible operon is one that is