rokaryoticgeneregulation：原核基因表達調(diào)控-展示頁
2025-01-21 08:18本頁面
【正文】 active repressor Tryptophan absent, repressor inactive, operon on Polycistronic* mRNA trpE trpD trpC trpB trpA Operator Start codon Stop codon trp operon Genes of operon E Polypeptides that make up enzymes for tryptophan synthesis D C B A 5? * = mRNA carries the information of several genes, which are translated into several proteins LE 1821b_1 DNA Protein Tryptophan (corepressor) Tryptophan present, repressor active, operon off mRNA Active repressor LE 1821b_2 DNA Protein Tryptophan (corepressor) Tryptophan present, repressor active, operon off mRNA Active repressor No RNA made Copyright 169。 2022 Pearson Education, Inc. publishing as Benjamin Cummings Learning Objectives ? understand that regulation of gene expression is a means by which to control timing and rate of generation regarding functional gene product (either RNA or polypeptide/protein). ? explain the concept of an operon in terms of ponents’ functions (promoter, operator, repressor, corepressor, inducer, gene cluster, polycistronic transcript). ? pare and contrast repressible and inducible operon systems/pathways. ? pare and contrast negative versus positive regulation of operons ? apply the operon concept to gene expression as it relates to geic engineering (specifically, our cloning and expression of the “tomato” gene). Copyright 16
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